Concepedia

A new phospholipase-C–calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

Martina Schmidt, Sandrine Evellin, Paschal A. Oude Weernink, F. vom Dorp, Holger Rehmann, Jon W. Lomasney, Karl H. Jakobs

Nature Cell Biology · 2001 · 346 citations · 24 references

DOI

Concepts

References

24

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

Johan de Rooij, Fried Zwartkruis, Mark H. G. Verheijen et al. · Nature · 1998 · 2K citations

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Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

Takashi Chijiwa, Akihiko Mishima, Masatoshi Hagiwara et al. · Journal of Biological Chemistry · 1990 · 1.5K citations · Full text

, , +14

Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A

Yehia Daaka, Louis M. Luttrell, Robert J. Lefkowitz · Nature · 1997 · 1.3K citations

, , +16

Glucosylation of Rho proteins by Clostridium difficile toxin B

Ingo Just, Jörg Selzer, Matthias Wilm et al. · Nature · 1995 · 1K citations

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Mechanism of Regulation of the Epac Family of cAMP-dependent RapGEFs

Johan de Rooij, Holger Rehmann, Miranda van Triest et al. · Journal of Biological Chemistry · 2000 · 396 citations · Full text

, , +16