Concepedia

Regulation of Transcription Functions of the p53 Tumor Suppressor by the mdm-2 Oncogene

Jiandong Chen, Jiayuh Lin, Arnold J. Levine

Molecular Medicine · 1995 · 214 citations · 47 references

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References

47

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

, , +14

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

Elisheva Yonish-Rouach, Dalia Resnftzky, Joseph Lotem et al. · Nature · 1991 · 2.1K citations

, , +13