Jiayuh Lin

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.

Jiayuh Lin, Jiandong Chen, Brian Elenbaas et al. · Genes & Development · 1994 · 649 citations · Full text

Tumor Biology, Protein Function, Amino Acids +13

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

Hui Song, Renxiao Wang, Shaomeng Wang et al. · Proceedings of the National Academy of Sciences · 2005 · 497 citations · Full text

Breast Oncology, Engineering, Tumor Biology +19

mdm-2 Inhibits the G₁ Arrest and Apoptosis Functions of the p53 Tumor Suppressor Protein

Jiandong Chen, Xiangwei Wu, Jiayuh Lin et al. · Molecular and Cellular Biology · 1996 · 351 citations · Full text

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer–Initiating Cells

Li Lin, Aiguo Liu, Zhengang Peng et al. · Cancer Research · 2011 · 302 citations · Full text

Chemoprevention Strategy, Stat3 Inhibitory Strategies, Immunology +17

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

William M. Burke, Xiaohong Jin, Huey-Jen Lin et al. · Oncogene · 2001 · 272 citations

Medicine, Breast Cancer Cells, Cancer Cell Biology +11