Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

Natural Sciences, Reactive Oxygen Specie, Molecular Biology +1

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

Zhong Zhong, Zilong Wen, James Darnell · Science · 1994 · 2.1K citations

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.6K citations · Full text

Cell Regulation, Constitutive Activation, Medicine +8

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

Naftaly Meydan, T Grunberger, Harjit Dadi et al. · Nature · 1996 · 910 citations

Hematological Malignancy, Malignant Blood Disorder, Immunology +4

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Roy Garcia, Tammy Bowman, Guilian Niu et al. · Oncogene · 2001 · 761 citations

Signal Transduction, Signaling Pathway, Cell Regulation +14