Concepedia

The switch of tau protein to an Alzheimer‐like state includes the phosphorylation of two serine‐proline motifs upstream of the microtubule binding region.

Jacek Biernat, Eckhard Mandelkow�, Christian Schröter, B. Lichtenberg-Kraag, Barbara Steiner, Barbara Berling, Helmut E. Meyer, Marc Mercken, Andrée Marie Vandermeeren, Michel Goedert

The EMBO Journal · 1992 · 480 citations · 20 references

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20

[6] Use of T7 RNA polymerase to direct expression of cloned genes

F. William Studier, Alan H. Rosenberg, John J. Dunn et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 1990 · 6.6K citations · Full text

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Michel Goedert, Maria Grazia Spillantini, Ross Jakes et al. · Neuron · 1989 · 2.5K citations

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The distribution of tau in the mammalian central nervous system.

Lester I. Binder, Anthony Frankfurter, L I Rebhun · The Journal of Cell Biology · 1985 · 1.6K citations · Full text

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A68: a Major Subunit of Paired Helical Filaments and Derivatized Forms of Normal Tau

Virginia M.‐Y. Lee, Brian J. Balin, László Ötvös et al. · Science · 1991 · 1.4K citations

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