Marc Mercken

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

Christopher Janus, Jacqueline Pearson, JoAnne McLaurin et al. · Nature · 2000 · 1.4K citations

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +10

Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease

Wai Haung Yu, Ana María Cuervo, Asok Kumar et al. · The Journal of Cell Biology · 2005 · 958 citations · Full text

A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

Lorenzo M. Refolo, Miguel A. Pappolla, John J. LaFrancois et al. · Neurobiology of Disease · 2001 · 516 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +7

Detection of Proteins in Normal and Alzheimer's Disease Cerebrospinal Fluid with a Sensitive Sandwich Enzyme‐Linked Immunosorbent Assay

Marc Vandermeeren, Marc Mercken, Eugeen Vanmechelen et al. · Journal of Neurochemistry · 1993 · 490 citations

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region.

Jacek Biernat, Eckhard Mandelkow�, Christian Schröter et al. · The EMBO Journal · 1992 · 477 citations · Full text

Alzheimer-like State, Molecular Biology, Neurochemical Biomarkers +16