John J. LaFrancois

Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester et al. · Neurobiology of Disease · 2000 · 992 citations · Full text

Alzheimer's Disease, Dementia, Vascular Dementia +12

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration<i>in vivo</i>

Wendy Noble, Emmanuel Planel, Cindy Zehr et al. · Proceedings of the National Academy of Sciences · 2005 · 687 citations · Full text

A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

Lorenzo M. Refolo, Miguel A. Pappolla, John J. LaFrancois et al. · Neurobiology of Disease · 2001 · 516 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +7

Cdk5 Is a Key Factor in Tau Aggregation and Tangle Formation In Vivo

Wendy Noble, Vicki Olm, Kazuyuki Takata et al. · Neuron · 2003 · 500 citations · Full text

Tau Aggregation, Protein Function, Signal Transduction +14

Novel Therapeutic Approach for the Treatment of Alzheimer's Disease by Peripheral Administration of Agents with an Affinity to β-Amyloid

Yasuji Matsuoka, John J. LaFrancois, Mariko Saito et al. · Journal of Neuroscience · 2003 · 324 citations · Full text

Immunology, Neurochemical Biomarkers, Immunotherapy +18