Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 181.5K citations

Life Sciences, Molecular Biology, Molecular Genetics +9

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi et al. · Nature Medicine · 2007 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +13

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase ₁  gene

Venugopal Radjendirane, Anil K. Jaiswal · Proceedings of the National Academy of Sciences · 1996 · 1K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Ischemic–Type Biliary Complications After Orthotopic Liver Transplantation

L. Sanchez-Urdazpal, Gregory J. Gores, Ellen MacDonald Ward et al. · Hepatology · 1992 · 430 citations · Full text

Medicine, Immunology, Surgery +17

Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress

Kei-ichi Fukuda, Sadamitsu Asoh, Masahiro Ishikawa et al. · Biochemical and Biophysical Research Communications · 2007 · 410 citations

Pharmacy, Biochemistry, Toxicology +16