Concepedia

S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process.

Andrea Bottaro, Rusty Lansford, Jun Zhang, Paul B. Rothman, Frederick W. Alt

The EMBO Journal · 1994 · 212 citations · 52 references

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52

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

, , +14

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

Clifford M. Snapper, William E. Paul · Science · 1987 · 1.9K citations

, , +17

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

, , +15

Generation and Analysis of Interleukin-4 Deficient Mice

Ralf Kühn, Klaus Rajewsky, Werner Müller · Science · 1991 · 1.3K citations

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Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

Hua Gu, Yong‐Rui Zou, Klaus Rajewsky · Cell · 1993 · 999 citations

, , +16