Concepedia

Ciprofloxacin Strongly Inhibits Clozapine Metabolism

E. E. M. Brouwers, Maaike Söhne, Saskia Kuipers, E.C.M. van Gorp, J. Schellens, Cornelis H.W. Koks, Jos H. Beijnen, Alwin D. R. Huitema

Clinical Drug Investigation · 2008 · 46 citations · 9 references

DOI

Concepts

References

9

Proposal for a New Tool to Evaluate Drug Interaction Cases

John R. Horn, Philip D. Hansten, Lingtak‐Neander Chan · Annals of Pharmacotherapy · 2007 · 577 citations

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Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test.

Leif Bertilsson, JA Carrillo, M-L Dahl et al. · British Journal of Clinical Pharmacology · 1994 · 308 citations · Full text

, , +15

Marked Elevations of Serum Creatine Kinase Activity Associated with Antipsychotic Drug Treatment

H.Y. Meltzer · Neuropsychopharmacology · 1996 · 168 citations · Full text

, , +11

Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2?mediated presystemic metabolism

Marika T. Granfors, Janne T. Backman, Mikko Neuvonen et al. · Clinical Pharmacology & Therapeutics · 2004 · 151 citations

, , +16

Inhibitory potency of quinolone antibacterial agents against cytochrome P450IA2 activity in vivo and in vitro

Uwe Fuhr, E M Anders, G. Mahr et al. · Antimicrobial Agents and Chemotherapy · 1992 · 136 citations · Full text

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