BioTheryX (United States)

Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity

Peter Schäfer, Anastasia Parton, Lori Capone et al. · Cellular Signalling · 2014 · 302 citations · Full text

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models

Waleed Minzel, Avanthika Venkatachalam, Avner Fink et al. · Cell · 2018 · 148 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors

Brian M. Dulmovits, Abena Appiah‐Kubi, Julien Papoin et al. · Blood · 2015 · 96 citations · Full text

BTX-1188, a first-in-class dual degrader of GSPT1 and IKZF1/3, for treatment of acute myeloid leukemia (AML) and solid tumors.

Aparajita H. Chourasia, Hannah Majeski, Angela Pasis et al. · Journal of Clinical Oncology · 2022 · 20 citations

Nm Btx-1188, Solid Tumors, Immunology +21

On Ternary Complex Stability in Protein Degradation: In Silico Molecular Glue Binding Affinity Calculations

Dahlia R. Weiss, Andrea Bortolato, Yongnian Sun et al. · Journal of Chemical Information and Modeling · 2023 · 20 citations