Avanthika Venkatachalam

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

Eliran Kadosh, Irit Snir-Alkalay, Avanthika Venkatachalam et al. · Nature · 2020 · 374 citations · Full text

Tumor Biology, Dysbiosis, Gut Microbiome Switches +9

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models

Waleed Minzel, Avanthika Venkatachalam, Avner Fink et al. · Cell · 2018 · 148 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

Atypical profiles and modulations of heme-enzymes catalyzed outcomes by low amounts of diverse additives suggest diffusible radicals' obligatory involvement in such redox reactions

Kelath Murali Manoj, Abhinav Parashar, Avanthika Venkatachalam et al. · Biochimie · 2016 · 75 citations

Biochemistry, Diffusible Radicals, Natural Sciences +11

Functioning of Microsomal Cytochrome P450s: Murburn Concept Explains the Metabolism of Xenobiotics in Hepatocytes

Kelath Murali Manoj, Abhinav Parashar, Sudeep Kumar Gade et al. · Frontiers in Pharmacology · 2016 · 72 citations · Full text

Redox Biology, Toxicological Mechanism, Oxidative Stress +21

Cyanide does more to inhibit heme enzymes, than merely serving as an active-site ligand

Abhinav Parashar, Avanthika Venkatachalam, Daniel Andrew Gideon et al. · Biochemical and Biophysical Research Communications · 2014 · 61 citations

Active-site Ligand, Molecular Pharmacology, Biochemistry +10