Leah Fung

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models

Waleed Minzel, Avanthika Venkatachalam, Avner Fink et al. · Cell · 2018 · 148 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +10

A novel fibroblast activation inhibitor attenuates left ventricular remodeling and preserves cardiac function in heart failure

Jessica Bradley, Pablo Spaletra, Zhen Li et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2018 · 20 citations · Full text

Cardiac Muscle, Heart Failure, Cardiovascular Function +16

BTX-1188, a first-in-class dual degrader of GSPT1 and IKZF1/3, for treatment of acute myeloid leukemia (AML) and solid tumors.

Aparajita H. Chourasia, Hannah Majeski, Angela Pasis et al. · Journal of Clinical Oncology · 2022 · 20 citations

Nm Btx-1188, Solid Tumors, Immunology +21

The novel protein homeostatic modulator BTX306 is active in myeloma and overcomes bortezomib and lenalidomide resistance

Jianxuan Zou, Richard J. Jones, Hua Wang et al. · Journal of Molecular Medicine · 2020 · 13 citations · Full text

Hematological Malignancy, Lenalidomide Resistance, Novel Therapy +6