Precision Nanosystems (Canada)

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

Nathan M. Belliveau, Jens Huft, Paulo J.C. Lin et al. · Molecular Therapy — Nucleic Acids · 2012 · 646 citations · Full text

Nanoparticles, Nanotherapeutics, Engineering +18

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

Alex K. K. Leung, Ismail M. Hafez, Svetlana Baoukina et al. · The Journal of Physical Chemistry C · 2012 · 344 citations

Nanoparticles, Proteinlipid Interaction, Engineering +17

Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing

Igor V. Zhigaltsev, Nathan M. Belliveau, Ismail M. Hafez et al. · Langmuir · 2012 · 332 citations

Nanoparticles, Lipid Preparation, Engineering +12

Manufacturing Considerations for the Development of Lipid Nanoparticles Using Microfluidics

Carla B. Roces, Gustavo Lou, Nikita Jain et al. · Pharmaceutics · 2020 · 276 citations · Full text

Using microfluidics for scalable manufacturing of nanomedicines from bench to GMP: A case study using protein-loaded liposomes

Cameron Webb, Neil S. Forbes, Carla B. Roces et al. · International Journal of Pharmaceutics · 2020 · 173 citations

Nanoparticles, Nanomedicine, Protein-loaded Liposomes +12