Pharminox (United Kingdom)

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities

Angela Rizzo, Sara Iachettini, Pasquale Zizza et al. · Journal of Experimental & Clinical Cancer Research · 2014 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Sara Iachettini, Malcolm F. G. Stevens, Mark Frigerio et al. · Journal of Experimental & Clinical Cancer Research · 2013 · 34 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Certain Imidazotetrazines Escape O6-Methylguanine-DNA Methyltransferase and Mismatch Repair

Jihong Zhang, Malcolm F. G. Stevens, Marc Hummersone et al. · Oncology · 2011 · 27 citations · Full text

Medicine, Oncology, Pharmacology +14

N3-Substituted Temozolomide Analogs Overcome Methylguanine-DNA Methyltransferase and Mismatch Repair Precipitating Apoptotic and Autophagic Cancer Cell Death

Jihong Zhang, Marc Hummersone, Charles S. Matthews et al. · Oncology · 2014 · 25 citations

Medicine, Oncology, Pharmacology +16

Quinol derivatives as potential trypanocidal agents

Amy S. Capes, Stephen Patterson, Susan Wyllie et al. · Bioorganic & Medicinal Chemistry · 2011 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14