Sara Iachettini

PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy

Erica Salvati, Marco Scarsella, Manuela Porru et al. · Oncogene · 2010 · 122 citations · Full text

Signal Transduction, Telomere-based Therapy, Molecular Biology +5

Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells

Sara Iachettini, Daniela Trisciuoglio, Dante Rotili et al. · Cell Death and Disease · 2018 · 106 citations · Full text

Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein

Jussara Amato, Linda Cerofolini, Diego Brancaccio et al. · Nucleic Acids Research · 2019 · 63 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +15

SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage

Angela Rizzo, Sara Iachettini, Erica Salvati et al. · Nucleic Acids Research · 2016 · 62 citations · Full text

Dna Damage, Molecular Regulation, Genomic Mechanism +16

<i>N</i>-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands Have Selective Antiproliferative Effects on Cancer Cells and Induce Telomere Damage

Valentina Casagrande, Erica Salvati, Antonello Alvino et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Induce Telomere Damage, Molecular Pharmacology, Medicinal Chemistry +12