Mark Frigerio

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

Sarah E. Golding, Elizabeth Rosenberg, Nicholas C.K. Valerie et al. · Molecular Cancer Therapeutics · 2009 · 389 citations · Full text

Medicine, Cancer Biology, Oncology +14

Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker

Marta Poblocka, Akang Leonard Bassey, Victoria M. Smith et al. · Scientific Reports · 2021 · 129 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab–MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios

Penny Bryant, Martin Pabst, George Badescu et al. · Molecular Pharmaceutics · 2015 · 122 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Enantioselective Formal Total Synthesis of the Antitumor Macrolide Bryostatin 7

Soraya Manaviazar, Mark Frigerio, Gurpreet Singh Bhatia et al. · Organic Letters · 2006 · 83 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

Pyranone, Thiopyranone, and Pyridone Inhibitors of Phosphatidylinositol 3-Kinase Related Kinases. Structure−Activity Relationships for DNA-Dependent Protein Kinase Inhibition, and Identification of the First Potent and Selective Inhibitor of the Ataxia Telangiectasia Mutated Kinase

Jonathan J. Hollick, Laurent Rigoreau, Céline Cano et al. · Journal of Medicinal Chemistry · 2007 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14