Concepedia

Aileron (United States)

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Statistics

Publications

60

Citations

17K

Authors

8

Location

Cambridge, United States

Aileron (United States) is a company institution in Cambridge, United States known for pharmacology, molecular oncology, and oncology.

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Publications

60

Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

Yong S. Chang, Bradford Graves, Vincent Guerlavais et al. · Proceedings of the National Academy of Sciences · 2013 · 661 citations · Full text

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Probing the α‐Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis

Zuojun Guo, Udayan Mohanty, Justin Noehre et al. · Chemical Biology & Drug Design · 2010 · 388 citations

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Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

Daniela Ben Neriah, Adrien Senecal, Lumie Benard et al. · Science Translational Medicine · 2018 · 250 citations · Full text

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Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development

Vincent Guerlavais, Tomi K. Sawyer, Luis A. Carvajal et al. · Journal of Medicinal Chemistry · 2023 · 125 citations · Full text

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Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models

Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie et al. · Nature Communications · 2018 · 114 citations · Full text

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1–5 of 60

Authors

8

  1. DA
    D. Allen Annis

    Aileron (United States), United States

    59 publications · 3.1K citations

    22

    h-index

  2. VG
    Vincent Guerlavais

    Aileron (United States), United States

    79 publications · 2K citations

    14

    h-index

  3. AA
    Allen Annis

    Aileron (United States), United States

    22 publications · 165 citations

    6

    h-index

  4. CE
    Carl Elkin

    Aileron (United States), United States

    10 publications · 872 citations

    6

    h-index

  5. MP
    Marie Payton

    Aileron (United States), United States

    7 publications · 128 citations

    4

    h-index

1–5 of 8