Carl Elkin

Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

Yong S. Chang, Bradford Graves, Vincent Guerlavais et al. · Proceedings of the National Academy of Sciences · 2013 · 661 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +15

Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development

Vincent Guerlavais, Tomi K. Sawyer, Luis A. Carvajal et al. · Journal of Medicinal Chemistry · 2023 · 125 citations · Full text

Medicine, Oncology, Pharmacology +14

Hydrogen Exchange-Mass Spectrometry Measures Stapled Peptide Conformational Dynamics and Predicts Pharmacokinetic Properties

Xiangguo Shi, Thomas E. Wales, Carl Elkin et al. · Analytical Chemistry · 2013 · 26 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

A scalable system to measure contrail formation on a per-flight basis

Scott Geraedts, Erica Brand, Thomas Dean et al. · Environmental Research Communications · 2023 · 25 citations · Full text

Natural Sciences, Aerospace Engineering, Meteorology +9

Feasibility test of per-flight contrail avoidance in commercial aviation

Aarón Sonabend, Carl Elkin, Thomas Dean et al. · Communications Engineering · 2024 · 14 citations · Full text

Engineering, Aerospace Engineering, Climate Change Mitigation +12