Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Louis Vermeulen, Felipe de Sousa e Melo, Maartje van der Heijden, +12

Nature Cell Biology

OncologyMedicineStem CellsBiological MicroenvironmentsColorectal Cancer +8

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

Susanne Kleber, Ignacio Sancho-Martinez, Benedikt Wiestler, +19

Cancer Cell

Neuro-oncologyPi3k Bind Cd95MedicineHigh-grade GliomasCell Biology +5

Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury

Deana Demjen, Susanne Kleber, Cecilia Zuliani, +9

Nature Medicine

Regenerative MedicineCell TherapyNeuroregenerationSpinal Cord InjuryMedicine +7

The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair

Nina S. Corsini, Ignacio Sancho-Martinez, Sabrina Laudenklos, +17

Cell stem cell

NeuroregenerationMedicineStem CellsCell DeathNeural Stem Cell +12

A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma

Wolfgang Wick, Harald Fricke, Klaus Junge, +15

Clinical Cancer Research

CD95-Ligand on Peripheral Myeloid Cells Activates Syk Kinase to Trigger Their Recruitment to the Inflammatory Site

Elisabeth Letellier, Sachin Kumar, Ignacio Sancho-Martinez, +18

Immunity

InflammationCytokineInflammatory SiteAutoimmune DiseaseImmunology +6

APG350 Induces Superior Clustering of TRAIL Receptors and Shows Therapeutic Antitumor Efficacy Independent of Cross-Linking via Fcγ Receptors

Christian Gieffers, Michael Kluge, Christian J. Merz, +10

Molecular Cancer Therapeutics

Cell DeathCancer BiologySignaling PathwayAnti-cancer AgentRadiation Oncology +17

Nanoscale FasL Organization on DNA Origami to Decipher Apoptosis Signal Activation in Cells

Ricarda Berger, Johann M. Weck, Simon Maximilian Kempe, +5

Small

Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients

Stefan Wieczorek, Sabine Hoffjan, Andrew Chan, +7

Genes and Immunity

ImmunogeneticsAutoimmune DiseaseGly307ser PolymorphismMedicineImmunodeficiencies +13

Survivin is regulated by interleukin‐4 in colon cancer stem cells

Anna Barbara Di Stefano, Flora Iovino, Ylenia Lombardo, +5

Journal of Cellular Physiology

Stem Cell HypothesisApoptosisImmunologyImmune RegulationCell Death +15