Concepedia

Yeast Surface Display Selection

Yeast Surface Display Selection is a laboratory technique in protein engineering that enables the isolation of high-affinity protein variants by coupling the expression of a protein library on the surface of yeast cells with selective pressure based on binding interactions.

96

Publications

5.6K

Citations

411

Authors

130

Institutions

Publications per year

2017–2026

29

Parents

Publications

96

Isolating and engineering human antibodies using yeast surface display

Wai Leung Lau, Benjamin J. Hackel, Stephen L. Sazinsky et al. · Nature Protocols · 2006 · 954 citations

, , +14

[25] Yeast surface display for directed evolution of protein expression, affinity, and stability

Eric T. Boder, K. Dane Wittrup · Methods in enzymology on CD-ROM/Methods in enzymology · 2000 · 328 citations

, , +14

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency 1 1Edited by J. A. Wells

Eric V. Shusta, Michele C. Kieke, Evan A. Parke et al. · Journal of Molecular Biology · 1999 · 231 citations

, , +7

Selection of functional T cell receptor mutants from a yeast surface-display library

Michele C. Kieke, Eric V. Shusta, Eric T. Boder et al. · Proceedings of the National Academy of Sciences · 1999 · 173 citations

, , +17

Engineering Antibody Affinity by Yeast Surface Display

David W. Colby, Brenda Kellogg, Christilyn Graff et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2004 · 140 citations

, , +14

1–5 of 96

Authors

411

  1. KD
    K. Dane Wittrup

    Massachusetts Institute of Technology, United States

    16 publications · 2.8K citations

    16

    h-index

  2. MU
    Mitsuyoshi Ueda

    Kyoto University, Japan

    10 publications · 403 citations

    10

    h-index

  3. BJ
    Benjamin J. Hackel

    University of Minnesota, United States

    7 publications · 1.3K citations

    7

    h-index

  4. AK
    Akihiko Kondo

    Kobe University, Japan

    5 publications · 101 citations

    5

    h-index

  5. EV
    Eric V. Shusta

    University of Wisconsin–Madison, United States

    4 publications · 504 citations

    4

    h-index

1–5 of 411

Institutions

130

  1. Massachusetts Institute of Technology

    Cambridge, United States

    13 h-index

    62 publications

    11.1K citations

  2. Kyoto University

    Kyoto, Japan

    10 h-index

    35 publications

    1.5K citations

  3. Kobe University

    Kobe, Japan

    7 h-index

    31 publications

    845 citations

  4. University of Nevada, Reno

    Reno, United States

    4 h-index

    5 publications

    78 citations

  5. Los Alamos National Laboratory

    Los Alamos, United States

    3 h-index

    13 publications

    300 citations

  6. University of Minnesota

    Minneapolis, United States

    3 h-index

    19 publications

    562 citations

  7. University of California, San Francisco

    San Francisco, United States

    3 h-index

    7 publications

    536 citations

  8. KAN Research Institute

    Kobe, Japan

    3 h-index

    7 publications

    99 citations

1–8 of 130

Venues

  1. Applied Microbiology and Biotechnology

    11 publications · 421 citations

    11

    h-index

  2. Methods in molecular biology

    Book series · 12 publications · 371 citations

    11

    h-index

  3. Journal of Molecular Biology

    JMB · 5 publications · 719 citations

    5

    h-index

  4. Protein Engineering Design and Selection

    PEDS · 4 publications · 152 citations

    4

    h-index

  5. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 3 publications · 527 citations

    3

    h-index

1–5