Concepedia

Vector Copy Number Testing

Vector Copy Number Testing is a molecular bioanalytical assay, within the broader category of viral vector characterization methods, that specifically quantifies the number of vector genomes integrated into or present per cell genome in gene therapy products to ensure consistency, safety, and potency during release testing.

33

Publications

2K

Citations

241

Authors

79

Institutions

Publications per year

2017–2026

15

Parents

Publications

33

A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants

Victor M. Morales, Assar Bäckman, Michael Bagdasarian · Gene · 1991 · 506 citations

, , +13

Genetic Fate of Recombinant Adeno-Associated Virus Vector Genomes in Muscle

Bruce C. Schnepp, K. Reed Clark, Dori Klemanski et al. · Journal of Virology · 2003 · 260 citations · Full text

, , +13

Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population

Olga Kustikova, Anke Wahlers, Klaus Kühlcke et al. · Blood · 2003 · 187 citations

, , +11

Absolute Determination of Single-Stranded and Self-Complementary Adeno-Associated Viral Vector Genome Titers by Droplet Digital PCR

Martin Lock, Mauricio R. Alvira, Shu‐Jen Chen et al. · Human Gene Therapy Methods · 2013 · 168 citations

, , +13

Universal Real-Time PCR-Based Assay for Lentiviral Titration

Wojciech Barczak, Wiktoria Maria Suchorska, Katarzyna Kulcenty · Molecular Biotechnology · 2014 · 78 citations · Full text

, , +14

1–5 of 33

Authors

241

  1. AH
    Angela Hückelhoven‐Krauss

    University Hospital Heidelberg, Germany

    2 publications · 95 citations

    2

    h-index

  2. BN
    Brigitte Neuber

    Heidelberg University, Germany

    2 publications · 95 citations

    2

    h-index

  3. PR
    Philip R. Johnson

    National Institute of Allergy and Infectious Diseases, United States

    2 publications · 292 citations

    2

    h-index

  4. BC
    Bruce C. Schnepp

    Nationwide Children's Hospital, United States

    2 publications · 292 citations

    2

    h-index

  5. MS
    Maria‐Luisa Schubert

    Heidelberg University, Germany

    2 publications · 95 citations

    2

    h-index

1–5 of 241

Institutions

79

  1. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    11 publications

    804 citations

  2. Inserm

    Paris, France

    3 h-index

    22 publications

    672 citations

  3. Children's Hospital of Philadelphia

    Philadelphia, United States

    3 h-index

    8 publications

    138 citations

  4. The University of Tokyo

    Tokyo, Japan

    2 h-index

    8 publications

    292 citations

  5. Tokyo University of Science

    Tokyo, Japan

    2 h-index

    6 publications

    219 citations

  6. Cell and Gene Therapy Catapult

    London, United Kingdom

    2 h-index

    10 publications

    273 citations

  7. University of Washington

    Seattle, United States

    2 h-index

    7 publications

    366 citations

  8. University Hospital Heidelberg

    Heidelberg, Germany

    2 h-index

    25 publications

    1.2K citations

1–8 of 79

Venues

  1. Human Gene Therapy

    3 publications · 95 citations

    3

    h-index

  2. Molecular Therapy

    3 publications · 55 citations

    3

    h-index

  3. Human Gene Therapy Methods

    3 publications · 259 citations

    3

    h-index

  4. 3

    h-index

  5. The Journal of Gene Medicine

    2 publications · 72 citations

    2

    h-index

1–5