Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment

Anja Seckinger, Jose Antonio Delgado, Samuel Moser, +28

Cancer Cell

Hematological MalignancyCancer ImmunosurveillanceMultiple Myeloma TreatmentImmunologyImmune Checkpoint Inhibitor +6

Idelalisib for optimized CD19‐specific chimeric antigen receptor T cells in chronic lymphocytic leukemia patients

Sophia Stock, Rudolf Übelhart, Maria‐Luisa Schubert, +18

International Journal of Cancer

Ibrutinib for improved chimeric antigen receptor T‐cell production for chronic lymphocytic leukemia patients

Fuli Fan, Sophia Stock, Lei Wang, +11

International Journal of Cancer

Comparison of IL-2 vs IL-7/IL-15 for the generation of NY-ESO-1-specific T cells

Wenjie Gong, Jean‐Marc Hoffmann, Sophia Stock, +11

Cancer Immunology Immunotherapy

InflammationAutoimmune DiseaseT-regulatory CellImmune RegulationImmunology +8

Optimized Assessment of qPCR-Based Vector Copy Numbers as a Safety Parameter for GMP-Grade CAR T Cells and Monitoring of Frequency in Patients

Alexander Kunz, Ulrike Gern, Anita Schmitt, +9

Molecular Therapy — Methods & Clinical Development

Third-Generation CAR T Cells Targeting CD19 Are Associated with an Excellent Safety Profile and Might Improve Persistence of CAR T Cells in Treated Patients

Maria‐Luisa Schubert, Anita Schmitt, Brigitte Neuber, +10

Blood

Pre-sensitization of Malignant B Cells Through Venetoclax Significantly Improves the Cytotoxic Efficacy of CD19.CAR-T Cells

Mingya Yang, Lei Wang, Ming Ni, +15

Frontiers in Immunology

T Cell TherapyCell TherapyImmunologyVenetoclax SignificantlyImmunotherapy +17

Lenalidomide Enhances Antigen-Specific Activity and Decreases CD45RA Expression of T Cells from Patients with Multiple Myeloma

Brigitte Neuber, Isabelle Herth, Claudia Tolliver, +8

The Journal of Immunology

Treatment of patients with relapsed or refractory CD19+ lymphoid disease with T lymphocytes transduced by RV-SFG.CD19.CD28.4-1BBzeta retroviral vector: a unicentre phase I/II clinical trial protocol

Maria‐Luisa Schubert, Anita Schmitt, Leopold Sellner, +13

BMJ Open

Sensitivity and Specificity of CD19.CAR-T Cell Detection by Flow Cytometry and PCR

Nicola Schanda, Tim Sauer, Alexander Kunz, +10

Cells

EngineeringImmunologyTransduction EfficiencyPathologyImmunodominance +24