Concepedia

Vector Biodistribution Modeling

Vector Biodistribution Modeling is a computational or mathematical framework that characterizes the spatial and temporal distribution of gene delivery vectors within biological tissues to predict targeting efficiency and off-target accumulation in the context of target tissue selection.

5

Publications

207

Citations

45

Authors

19

Institutions

Publications per year

2017–2026

1

Parents

Publications

5

Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered to Alveolar Bone Defects Exhibits Safety and Biodistribution Profiles Favorable for Clinical Use

Po‐Chun Chang, Joni Augusto Cirelli, Qiming Jin et al. · Human Gene Therapy · 2009 · 87 citations · Full text

, , +16

Comparative analysis of vector biodistribution, persistence and gene expression following intravenous delivery of bovine, porcine and human adenoviral vectors in a mouse model

Anurag Sharma, Dinesh S. Bangari, Manish Tandon et al. · Virology · 2009 · 46 citations · Full text

, , +17

Unexpected Death of a Duchenne Muscular Dystrophy Patient in an N-of-1 Trial of rAAV9-delivered CRISPR-transactivator

Angela Lek, Brenda Wong, Allison M. Keeler et al. · medRxiv · 2023 · 34 citations · Full text

, , +17

Gene therapy: progress and challenges.

Frauke Meyer, M H Finer · PubMed · 2001 · 23 citations

, , +16

Biodistribution and Shedding of AAV Vectors

Caroline Le Guiner, Valder R. Arruda · Methods in molecular biology · 2011 · 17 citations

, , +10

1–5 of 5

Authors

45

  1. AP
    Aseem Pandey

    Purdue University West Lafayette, United States

    1 publications · 46 citations

    1

    h-index

  2. TD
    Theodora Danciu

    University of Michigan, United States

    1 publications · 87 citations

    1

    h-index

  3. QJ
    Qiming Jin

    University of Michigan, United States

    1 publications · 87 citations

    1

    h-index

  4. WV
    William V. Giannobile

    University of Michigan, United States

    1 publications · 87 citations

    1

    h-index

  5. BA
    Barbara A. Sosnowski

    Selective Genetics (United States), United States

    1 publications · 87 citations

    1

    h-index

1–5 of 45

Institutions

19

  1. Inserm

    Paris, France

    1 h-index

    2 publications

    34 citations

  2. Tartu University Hospital

    Tartu, Estonia

    1 h-index

    1 publications

    34 citations

  3. University of Michigan

    Ann Arbor, United States

    1 h-index

    8 publications

    696 citations

  4. University of Massachusetts Chan Medical School

    Worcester, United States

    1 h-index

    10 publications

    340 citations

  5. Purdue University West Lafayette

    West Lafayette, United States

    1 h-index

    6 publications

    276 citations

  6. Yale University

    New Haven, United States

    1 h-index

    6 publications

    204 citations

  7. Advanced Tissue (United States)

    Little Rock, United States

    1 h-index

    2 publications

    174 citations

  8. Cooperative Research Centre for Tissue Growth and Repair

    Adelaide, Australia

    1 h-index

    2 publications

    174 citations

1–8 of 19

Venues

  1. Human Gene Therapy

    1 publications · 87 citations

    1

    h-index

  2. medRxiv

    Repository · 1 publications · 34 citations

    1

    h-index

  3. PubMed

    Repository · 1 publications · 23 citations

    1

    h-index

  4. Methods in molecular biology

    Book series · 1 publications · 17 citations

    1

    h-index

  5. Virology

    1 publications · 46 citations

    1

    h-index

1–5