Concepedia

Target Tissue Selection

Target Tissue Selection is a strategic design process in gene therapy translation that determines and prioritizes the specific tissue or cell population to be targeted for gene delivery on the basis of disease pathophysiology, vector tropism, accessibility, and safety and efficacy considerations.

31

Publications

1.7K

Citations

180

Authors

82

Institutions

Publications per year

2017–2026

10

Parents

Children

Publications

31

Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations

C A Torres, Akiko Iwasaki, Brian H. Barber et al. · The Journal of Immunology · 1997 · 277 citations

, , +13

A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection

Lin Yang, Jiangang Jiang, Lauren M. Drouin et al. · Proceedings of the National Academy of Sciences · 2009 · 210 citations

, , +17

Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types

Sripriya Ravindra Kumar, Timothy F. Miles, Xinhong Chen et al. · Nature Methods · 2020 · 203 citations · Full text

, , +9

Reference gene selection for real-time RT-PCR in regenerating mouse livers

Kohei Tatsumi, Kazuo Ohashi, Sanae Taminishi et al. · Biochemical and Biophysical Research Communications · 2008 · 93 citations

, , +13

Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries

Jakob Körbelin, Timo Sieber, Stefan Michelfelder et al. · Molecular Therapy · 2016 · 92 citations · Full text

, , +17

1–5 of 31

Authors

180

  1. TD
    Tatyana Dobreva

    California Institute of Technology, United States

    3 publications · 281 citations

    3

    h-index

  2. MT
    Martin Trepel

    University Medical Center Hamburg-Eppendorf, Germany

    3 publications · 185 citations

    3

    h-index

  3. VG
    Viviana Gradinaru

    California Institute of Technology, United States

    3 publications · 281 citations

    3

    h-index

  4. DA
    David Alan Brown

    California Institute of Technology, United States

    3 publications · 281 citations

    3

    h-index

  5. SC
    Sisi Chen

    California Institute of Technology, United States

    2 publications · 78 citations

    2

    h-index

1–5 of 180

Institutions

82

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    11 publications

    2.2K citations

  2. California Institute of Technology

    Pasadena, United States

    3 h-index

    27 publications

    3.2K citations

  3. University Medical Center Hamburg-Eppendorf

    Hamburg, Germany

    2 h-index

    8 publications

    574 citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    12 publications

    434 citations

  5. University Hospital Augsburg

    Augsburg, Germany

    2 h-index

    2 publications

    103 citations

  6. University Hospital Cologne

    Cologne, Germany

    2 h-index

    3 publications

    150 citations

  7. University Cancer Center Hamburg

    Hamburg, Germany

    2 h-index

    8 publications

    574 citations

  8. Universität Hamburg

    Hamburg, Germany

    2 h-index

    8 publications

    574 citations

1–8 of 82

Venues

  1. Scientific Reports

    3 publications · 87 citations

    3

    h-index

  2. Molecular Therapy

    2 publications · 136 citations

    2

    h-index

  3. 1

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 1 publications · 93 citations

    1

    h-index

  5. BioTechniques

    1 publications · 27 citations

    1

    h-index

1–5