Concepedia

Vector Biodistribution

Vector Biodistribution is a methodological framework in vector design that specifies the spatial and temporal distribution patterns of vectors within biological systems, distinguishing it from related methods by its focus on quantifying targeting efficiency and off-target accumulation in vivo.

40

Publications

2K

Citations

369

Authors

89

Institutions

Publications per year

2017–2026

15

Parents

Publications

40

Influence of Pre-existing Anti-capsid Neutralizing and Binding Antibodies on AAV Vector Transduction

Zachary Fitzpatrick, Christian Leborgne, Elena Barbon et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 197 citations · Full text

, , +13

Lack of Germline Transmission of Vector Sequences Following Systemic Administration of Recombinant AAV-2 Vector in Males

Valder R. Arruda, Paul Fields, Ross Milner et al. · Molecular Therapy · 2001 · 154 citations · Full text

, , +14

Cell-Selective Adeno-Associated Virus-Mediated <i>SCN1A</i> Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates

Annie Tanenhaus, T. D. Stowe, Andrew L. Young et al. · Human Gene Therapy · 2022 · 121 citations · Full text

, , +17

Route of Administration Determines Induction of T-Cell-Independent Humoral Responses to Adeno-Associated Virus Vectors

Weidong Xiao, Narendra Chirmule, John Tazelaar et al. · Molecular Therapy · 2000 · 114 citations · Full text

, , +17

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates

Immanuel P. Seitz, Stylianos Michalakis, Barbara Wilhelm et al. · Investigative Ophthalmology & Visual Science · 2017 · 109 citations · Full text

, , +14

1–5 of 40

Authors

369

  1. JM
    James M. Wilson

    University of Pennsylvania, United States

    3 publications · 175 citations

    3

    h-index

  2. FM
    Federico Mingozzi

    Children's Hospital of Philadelphia, United States

    3 publications · 337 citations

    3

    h-index

  3. VR
    Valder R. Arruda

    Children's Hospital of Philadelphia, United States

    3 publications · 195 citations

    3

    h-index

  4. RJ
    R. Jude Samulski

    University of North Carolina at Chapel Hill, United States

    2 publications · 53 citations

    2

    h-index

  5. FM
    Fulvio Mavilio

    University of Modena and Reggio Emilia, Italy

    2 publications · 161 citations

    2

    h-index

1–5 of 369

Institutions

89

  1. Inserm

    Paris, France

    6 h-index

    35 publications

    3.9K citations

  2. University of Florida

    Gainesville, United States

    6 h-index

    32 publications

    1.4K citations

  3. Genethon (France)

    Évry-Courcouronnes, France

    6 h-index

    34 publications

    3.5K citations

  4. University of Pennsylvania

    Philadelphia, United States

    5 h-index

    35 publications

    1.9K citations

  5. Sorbonne Université

    Paris, France

    4 h-index

    9 publications

    1.1K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    11 publications

    394 citations

  7. University of Washington

    Seattle, United States

    4 h-index

    20 publications

    1.2K citations

  8. Children's Hospital of Philadelphia

    Philadelphia, United States

    4 h-index

    15 publications

    1.3K citations

1–8 of 89

Venues

  1. Human Gene Therapy

    9 publications · 458 citations

    9

    h-index

  2. Molecular Therapy

    7 publications · 586 citations

    7

    h-index

  3. 5

    h-index

  4. The Journal of Gene Medicine

    4 publications · 105 citations

    4

    h-index

  5. PLoS ONE

    3 publications · 56 citations

    3

    h-index

1–5