AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye

Felix F. Reichel, Daniyar Dauletbekov, Reinhild Klein, +10

Molecular Therapy

AllergyAdaptive Immune SystemAdaptive Immune ResponseInnate Immune SystemImmunology +5

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates

Immanuel P. Seitz, Stylianos Michalakis, Barbara Wilhelm, +9

Investigative Ophthalmology & Visual Science

Single Subretinal InjectionsVector GenomesImmunodeficienciesViral PathogenesisPathology +18

Out-of-pocket Costs for Individuals with Atopic Eczema: A Cross-sectional Study in Nine European Countries

Alexander Zink, B.W.M. Arents, A. Fink‐Wagner, +5

Acta Dermato Venereologica

AsthmaAllergy MedicineAtopic EczemaSkin AllergyDermatology +18

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia

Manuel Fischer, G. Alex Ochakovski, Benjamin Beier, +13

JAMA Ophthalmology

Three-year results of phase I retinal gene therapy trial for CNGA3-mutated achromatopsia: results of a non randomised controlled trial

Felix F. Reichel, Stylianos Michalakis, Barbara Wilhelm, +19

British Journal of Ophthalmology

Development of retinal atrophy after subretinal gene therapy with voretigene neparvovec

Felix F. Reichel, Immanuel P. Seitz, Fabian Wozar, +11

British Journal of Ophthalmology

CHANGES IN RETINAL SENSITIVITY AFTER GENE THERAPY IN CHOROIDEREMIA

M. Dominik Fischer, G. Alex Ochakovski, Benjamin Beier, +13

Retina

Multimodal assessment of choroideremia patients defines pre-treatment characteristics

Immanuel P. Seitz, Ahmad Zhour, Susanne Kohl, +7

Graefe s Archive for Clinical and Experimental Ophthalmology

Clinical EvidenceChoroideremia PatientsDisease AssessmentClinical EvaluationAssessment +1

High Symmetry of Visual Acuity and Visual Fields in <i>RPGR</i>-Linked Retinitis Pigmentosa

Julia-Sophia Bellingrath, G. Alex Ochakovski, Immanuel P. Seitz, +9

Investigative Ophthalmology & Visual Science

Development of Methodology and Study Protocol: Safety and Efficacy of a Single Subretinal Injection of rAAV.hCNGA3 in Patients with<i>CNGA3</i>-Linked Achromatopsia Investigated in an Exploratory Dose-Escalation Trial

Nadine Kahle, Tobias Peters, Ditta Zobor, +13

Human Gene Therapy Clinical Development

Ocular DiseaseOphthalmologyExperimental OphthalmologyClinical TrialsExploratory Dose-escalation Trial +11