Concepedia

Uricase Therapy

Uricase Therapy is a therapeutic enzyme treatment that catalyzes the oxidation of uric acid into the more soluble compound allantoin, thereby reducing serum urate levels in patients with refractory gout or hyperuricemia.

79

Publications

5.2K

Citations

444

Authors

145

Institutions

Publications per year

2017–2026

31

Parents

Publications

79

Efficacy and Tolerability of Pegloticase for the Treatment of Chronic Gout in Patients Refractory to Conventional Treatment

John S. Sundy, Herbert S. B. Baraf, Robert A. Yood et al. · JAMA · 2011 · 516 citations · Full text

, , +14

Recombinant Urate Oxidase for the Prophylaxis or Treatment of Hyperuricemia in Patients With Leukemia or Lymphoma

Ching‐Hon Pui, Hazem H. Mahmoud, Joseph M. Wiley et al. · Journal of Clinical Oncology · 2001 · 365 citations

, , +13

Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase

Nancy J. Ganson, Susan J. Kelly, Edna Scarlett et al. · Arthritis Research & Therapy · 2005 · 343 citations · Full text

, , +14

Hyperuricemia Causes Glomerular Hypertrophy in the Rat

Takahiko Nakagawa, Marilda Mazzali, Duk‐Hee Kang et al. · American Journal of Nephrology · 2002 · 271 citations

, , +12

Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout

Peter E. Lipsky, Leonard H. Calabrese, Arthur Kavanaugh et al. · Arthritis Research & Therapy · 2014 · 261 citations · Full text

, , +15

1–5 of 79

Authors

444

  1. RT
    Robert Terkeltaub

    University of California San Diego, United States

    6 publications · 319 citations

    6

    h-index

  2. PE
    Peter E. Lipsky

    The University of Texas Southwestern Medical Center, United States

    5 publications · 891 citations

    5

    h-index

  3. JS
    John S. Sundy

    Duke Medical Center, United States

    5 publications · 1.5K citations

    5

    h-index

  4. HS
    Herbert S. B. Baraf

    Center for Rheumatology, United States

    4 publications · 743 citations

    4

    h-index

  5. AK
    Alan Kivitz

    Altoona Center for Clinical Research, United States

    4 publications · 112 citations

    4

    h-index

1–5 of 444

Institutions

145

  1. Chongqing Medical University

    Chongqing, China

    9 h-index

    58 publications

    2.5K citations

  2. Duke Medical Center

    Durham, United States

    6 h-index

    10 publications

    2.9K citations

  3. University of California San Diego

    San Diego, United States

    6 h-index

    9 publications

    601 citations

  4. Duke University

    Durham, United States

    6 h-index

    14 publications

    2K citations

  5. Army Medical University

    Chongqing, China

    4 h-index

    5 publications

    168 citations

  6. Selecta Biosciences (United States)

    Watertown, United States

    4 h-index

    20 publications

    582 citations

  7. Altoona Center for Clinical Research

    Duncansville, United States

    4 h-index

    4 publications

    112 citations

  8. Massachusetts General Hospital

    Boston, United States

    4 h-index

    12 publications

    479 citations

1–8 of 145

Venues

  1. PubMed

    Repository · 5 publications · 165 citations

    5

    h-index

  2. Annals of the Rheumatic Diseases

    ARD · 3 publications · 56 citations

    3

    h-index

  3. PLoS ONE

    3 publications · 129 citations

    3

    h-index

  4. Rheumatology and Therapy

    3 publications · 69 citations

    3

    h-index

  5. Arthritis Research & Therapy

    3 publications · 653 citations

    3

    h-index

1–5