Concepedia

Ultra-high-throughput Screening

Ultra-High-Throughput Screening is a high-throughput experimental methodology in drug discovery and functional genomics that distinguishes itself by enabling the rapid, automated testing of millions to billions of chemical or biological compounds per day to identify active agents against specific molecular targets.

141

Publications

8.8K

Citations

898

Authors

264

Institutions

Publications per year

2017–2026

51

Variants

Uhts

Parents

Publications

141

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

Jeremy J. Agresti, Eugene Antipov, Adam R. Abate et al. · Proceedings of the National Academy of Sciences · 2010 · 1.2K citations · Full text

, , +17

An open-source drug discovery platform enables ultra-large virtual screens

Christoph Gorgulla, Andras Boeszoermenyi, Zifu Wang et al. · Nature · 2020 · 645 citations · Full text

, , +11

An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome

Chenxu Zhu, Miao Yu, Hui Huang et al. · Nature Structural & Molecular Biology · 2019 · 380 citations · Full text

, , +14

Ultrahigh-throughput–directed enzyme evolution by absorbance-activated droplet sorting (AADS)

Fabrice Gielen, Raphaëlle Hours, Stéphane Emond et al. · Proceedings of the National Academy of Sciences · 2016 · 275 citations · Full text

, , +13

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F

Regina Cencic, David R. Hall, Françis Robert et al. · Proceedings of the National Academy of Sciences · 2010 · 180 citations · Full text

, , +17

1–5 of 141

Authors

898

  1. FH
    Florian Hollfelder

    University of Cambridge, United Kingdom

    7 publications · 447 citations

    7

    h-index

  2. BS
    Berta Strulovici

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    6 publications · 182 citations

    6

    h-index

  3. OK
    Oleg Kornienko

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    5 publications · 160 citations

    5

    h-index

  4. AJ
    Andrew J. Pope

    GlaxoSmithKline (United Kingdom), United Kingdom

    5 publications · 211 citations

    5

    h-index

  5. DA
    David A. Dunn

    Auburn University, United States

    4 publications · 190 citations

    4

    h-index

1–5 of 898

Institutions

264

  1. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    30 publications

    2.1K citations

  2. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    6 h-index

    61 publications

    1.7K citations

  3. Harvard University

    Cambridge, United States

    5 h-index

    28 publications

    12.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    21 publications

    1.6K citations

  5. Université de Strasbourg

    Strasbourg, France

    5 h-index

    21 publications

    3.7K citations

  6. Scripps Research Institute

    San Diego, United States

    4 h-index

    29 publications

    854 citations

  7. Durham University

    Durham, United Kingdom

    3 h-index

    7 publications

    187 citations

  8. RWTH Aachen University

    Aachen, Germany

    3 h-index

    6 publications

    451 citations

1–8 of 264

Venues

  1. SLAS DISCOVERY

    19 publications · 813 citations

    17

    h-index

  2. Assay and Drug Development Technologies

    10 publications · 380 citations

    10

    h-index

  3. Drug Discovery Today

    6 publications · 312 citations

    6

    h-index

  4. Scientific Reports

    5 publications · 208 citations

    5

    h-index

  5. PLoS ONE

    4 publications · 190 citations

    4

    h-index

1–5