Single-cell multimodal omics: the power of many

Chenxu Zhu, Bing Ren

Nature Methods

MedicineMulti-omics StudyMulti-omicsSingle-cell BiologyOmics Technology +6

An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome

Chenxu Zhu, Miao Yu, Hui Huang, +7

Nature Structural & Molecular Biology

Molecular BiologyTranscriptomics TechnologySingle-cell Joint AnalysisEpigeneticsSingle Cell Sequencing +14

Joint profiling of histone modifications and transcriptome in single cells from mouse brain

Chenxu Zhu, Yanxiao Zhang, Yang Eric Li, +3

Nature Methods

Histone ModificationsChromatinFunctional GenomicsJoint ProfilingSingle Cell Sequencing +10

Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution

Chenxu Zhu, Yun Gao, Hongshan Guo, +7

Cell stem cell

Cell LineageDevelopmental BiologySingle-cell 5-Formylcytosine LandscapesCell SpecializationMammalian Early Embryos +9

A comparative atlas of single-cell chromatin accessibility in the human brain

Yang Eric Li, Michael Miller, Nicholas D. Johnson, +35

Science

Epigenetic ChangeGeneticsChromatin AccessibilityEpigeneticsComparative Atlas +22

Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation

Jinghui Song, Yuan Zhuang, Chenxu Zhu, +6

Nature Chemical Biology

Functional GenomicsHuman Pus10GeneticsMirna ProcessingRna Biology +7

Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution

Hu Zeng, Bo He, Bo Xia, +12

Journal of the American Chemical Society

Selective 5HmcEngineeringBiomolecular ToolDna AnalysisMolecular Biology +18

T Lymphocyte-Captured DNA Network for Localized Immunotherapy

Chi Yao, Chenxu Zhu, Jianpu Tang, +3

Journal of the American Chemical Society

Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain

Yanxiao Zhang, Maria Luisa Amaral, Chenxu Zhu, +7

Cell Research

Transposase-assisted tagmentation of RNA/DNA hybrid duplexes

Bo Lu, Liting Dong, Danyang Yi, +4

eLife