Concepedia

Two-dimensional Liquid Chromatography

Two-Dimensional Liquid Chromatography is a separation technique in which two distinct liquid chromatographic methods are sequentially coupled to enhance resolution and selectivity in the analysis of complex protein mixtures by exploiting orthogonal physicochemical properties for improved separation compared to one-dimensional approaches.

956

Publications

47.2K

Citations

3.6K

Authors

976

Institutions

Publications per year

2017–2026

251

Variants

2D Lc2D-lc

Parents

Publications

956

A new form of chromatogram employing two liquid phases

A. J. P. Martin, R. L. M. Synge · Biochemical Journal · 1941 · 1.6K citations · Full text

, , +12

Orthogonality of Separation in Two-Dimensional Liquid Chromatography

Martin Gilár, Petra Olivova, Amy E. Daly et al. · Analytical Chemistry · 2005 · 810 citations

, , +16

Peptide Separation by Two-dimensional Chromatography and Electrophoresis

Arnold M. Katz, William J. Dreyer, Christian B. Anfinsen · Journal of Biological Chemistry · 1959 · 731 citations · Full text

, , +17

Chromatography of <sup>32</sup>P‐Labelled Oligonucleotides on Thin Layers of DEAE‐Cellulose

G.G. Brownlee, Frederick Sanger · European Journal of Biochemistry · 1969 · 511 citations · Full text

, , +15

Preparation of Homopolymers and Block Copolymers in Miniemulsion by ATRP Using Activators Generated by Electron Transfer (AGET)

Ke Min, Haifeng Gao, Krzysztof Matyjaszewski · Journal of the American Chemical Society · 2005 · 463 citations

, , +17

1–5 of 956

Authors

3.6K

  1. PJ
    Peter J. Schoenmakers

    University of Amsterdam, Netherlands

    37 publications · 2.2K citations

    24

    h-index

  2. DR
    Dwight R. Stoll

    Gustavus Adolphus College, United States

    32 publications · 2.4K citations

    24

    h-index

  3. LM
    Luigi Mondello

    University of Messina, Italy

    29 publications · 1.7K citations

    24

    h-index

  4. PD
    Paola Dugo

    University of Messina, Italy

    25 publications · 1.4K citations

    21

    h-index

  5. HP
    Harald Pasch

    Stellenbosch University, South Africa

    20 publications · 752 citations

    17

    h-index

1–5 of 3.6K

Institutions

976

  1. University of Amsterdam

    Amsterdam, The Netherlands

    27 h-index

    143 publications

    6.8K citations

  2. Chinese Academy of Sciences

    Beijing, China

    25 h-index

    257 publications

    8.8K citations

  3. University of Messina

    Messina, Italy

    24 h-index

    132 publications

    7.3K citations

  4. Gustavus Adolphus College

    Saint Peter, United States

    22 h-index

    57 publications

    3.6K citations

  5. Dalian Institute of Chemical Physics

    Dalian, China

    18 h-index

    151 publications

    4.6K citations

  6. University of Minnesota

    Minneapolis, United States

    17 h-index

    58 publications

    2.8K citations

  7. University of Michigan

    Ann Arbor, United States

    17 h-index

    85 publications

    5.4K citations

  8. Stellenbosch University

    Stellenbosch, South Africa

    16 h-index

    42 publications

    1.7K citations

1–8 of 976

Venues

  1. Journal of Chromatography A

    260 publications · 11.4K citations

    58

    h-index

  2. Analytical Chemistry

    93 publications · 8.2K citations

    48

    h-index

  3. Journal of Proteome Research

    JPR · 39 publications · 2.5K citations

    30

    h-index

  4. Journal of Separation Science

    53 publications · 2K citations

    26

    h-index

  5. Analytical and Bioanalytical Chemistry

    35 publications · 1.4K citations

    25

    h-index

1–5