Concepedia

Transporter-mediated Bioavailability

Transporter-Mediated Bioavailability is a pharmacokinetic determinant that quantifies the extent and rate at which a drug, subject to active transport by membrane transporters, reaches systemic circulation in a functionally available form, thereby distinguishing it from passive diffusion-driven bioavailability.

5

Publications

272

Citations

30

Authors

20

Institutions

Publications per year

2017–2026

2

Parents

Publications

5

Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40

Yorki Tayrouz, Reinhard Ding, Jürgen Burhenne et al. · Clinical Pharmacology & Therapeutics · 2003 · 95 citations

, , +16

Intracellular drug bioavailability: a new predictor of system dependent drug disposition

André Mateus, Andrea Treyer, Christine Wegler et al. · Scientific Reports · 2017 · 82 citations · Full text

, , +17

Role of n-methyl Pyrrolidone in the Enhancement of Aqueous Phase Transdermal Transport

Philip J. Lee, Róbert Langer, V. Prasad Shastri · Journal of Pharmaceutical Sciences · 2005 · 66 citations

, , +14

Cellular Uptake and Transport Mechanism of 6-Mercaptopurine Nanomedicines for Enhanced Oral Bioavailability

Yaru Zou, Wei Gao, Huizhen Jin et al. · International Journal of Nanomedicine · 2023 · 17 citations · Full text

, , +17

Pharmacokinetic simulations to explore dissolution criteria of BCS I and III biowaivers with and without MDR-1 efflux transporter

Hanna Kortejärvi, J. Malkki, Ramzi Shawahna et al. · European Journal of Pharmaceutical Sciences · 2014 · 12 citations

, , +15

1–5 of 5

Authors

30

  1. KR
    Klaus‐Dieter Riedel

    Heidelberg University, Germany

    1 publications · 95 citations

    1

    h-index

  2. RL
    Róbert Langer

    Massachusetts Institute of Technology, United States

    1 publications · 66 citations

    1

    h-index

  3. CW
    Christine Wegler

    Uppsala University, Sweden

    1 publications · 82 citations

    1

    h-index

  4. GM
    Gerd Mikus

    Heidelberg University, Germany

    1 publications · 95 citations

    1

    h-index

  5. LZ
    Libo Zhao

    Peking University, China

    1 publications · 17 citations

    1

    h-index

1–5 of 30

Institutions

20

  1. Peking University Third Hospital

    Beijing, China

    1 h-index

    1 publications

    17 citations

  2. Beijing Children’s Hospital

    Beijing, China

    1 h-index

    5 publications

    85 citations

  3. Université Paris Cité

    Paris, France

    1 h-index

    2 publications

    24 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    2 publications

    24 citations

  5. University of Helsinki

    Helsinki, Finland

    1 h-index

    4 publications

    48 citations

  6. Peking University

    Beijing, China

    1 h-index

    1 publications

    17 citations

  7. Inserm

    Paris, France

    1 h-index

    2 publications

    24 citations

  8. Délégation Paris 5

    Paris, France

    1 h-index

    2 publications

    24 citations

1–8 of 20

Venues

  1. Scientific Reports

    1 publications · 82 citations

    1

    h-index

  2. Journal of Pharmaceutical Sciences

    1 publications · 66 citations

    1

    h-index

  3. European Journal of Pharmaceutical Sciences

    1 publications · 12 citations

    1

    h-index

  4. International Journal of Nanomedicine

    1 publications · 17 citations

    1

    h-index

  5. Clinical Pharmacology & Therapeutics

    CPT · 1 publications · 95 citations

    1

    h-index

1–5