Concepedia

Translational Derepression

Translational Derepression is a regulatory mechanism in gene expression whereby the inhibition of translation initiation is relieved, leading to increased ribosomal loading and protein synthesis from specific mRNAs.

112

Publications

8.1K

Citations

438

Authors

143

Institutions

Publications per year

2017–2026

11

Parents

Publications

112

Short RNAs Repress Translation after Initiation in Mammalian Cells

Christian P. Petersen, Marie-Ève Bordeleau, Jerry Pelletier et al. · Molecular Cell · 2006 · 736 citations · Full text

, , +14

Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.

Jeong Han, Patricia A. Thompson, Bruce Beutler · The Journal of Experimental Medicine · 1990 · 508 citations · Full text

, , +17

Evidence for translational regulation of the activator of general amino acid control in yeast.

A G Hinnebusch · Proceedings of the National Academy of Sciences · 1984 · 483 citations · Full text

, , +17

Guanosine 5'-diphosphate 3'-diphosphate (ppGpp): positive effector for histidine operon transcription and general signal for amino-acid deficiency.

John C. Stephens, S W Artz, B N Ames · Proceedings of the National Academy of Sciences · 1975 · 238 citations · Full text

, , +17

Second messenger signalling governs <i>Escherichia coli</i> biofilm induction upon ribosomal stress

Alex Boehm, Samuel Steiner, F. Zaehringer et al. · Molecular Microbiology · 2009 · 237 citations

, , +17

1–5 of 112

Authors

438

  1. AG
    Alan G. Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    7 publications · 383 citations

    7

    h-index

  2. CR
    Carlos R. Vázquez de Aldana

    Universidad de Salamanca, Spain

    5 publications · 282 citations

    5

    h-index

  3. GT
    George Thireos

    Foundation for Research and Technology Hellas, Greece

    5 publications · 249 citations

    5

    h-index

  4. RC
    Ronald C. Wek

    Indiana University – Purdue University Indianapolis, United States

    3 publications · 193 citations

    3

    h-index

  5. AG
    A G Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    3 publications · 642 citations

    3

    h-index

1–5 of 438

Institutions

143

  1. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    10 h-index

    49 publications

    4.4K citations

  2. National Institutes of Health

    Bethesda, United States

    9 h-index

    43 publications

    4.4K citations

  3. Health and Human Development (2HD) Research Network

    Douala, Cameroon

    6 h-index

    22 publications

    1.7K citations

  4. University of Washington

    Seattle, United States

    5 h-index

    17 publications

    920 citations

  5. National Institute of Child Health

    Budapest, Hungary

    5 h-index

    17 publications

    1.5K citations

  6. Harvard University

    Cambridge, United States

    4 h-index

    10 publications

    448 citations

  7. McGill University

    Montreal, Canada

    3 h-index

    7 publications

    2.2K citations

  8. The University of Tokyo

    Tokyo, Japan

    3 h-index

    11 publications

    1.3K citations

1–8 of 143

Venues

  1. Molecular and Cellular Biology

    MCB · 15 publications · 816 citations

    14

    h-index

  2. Journal of Bacteriology

    JB · 14 publications · 448 citations

    13

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 1.2K citations

    8

    h-index

  4. Journal of Biological Chemistry

    JBC · 6 publications · 401 citations

    6

    h-index

  5. Molecular Cell

    5 publications · 1.3K citations

    5

    h-index

1–5