Concepedia

Translation Initiation Engineering

Translation Initiation Engineering is a methodological framework within protein expression engineering that specifically manipulates the regulatory elements and sequence contexts governing ribosome binding and start codon selection to optimize the efficiency and accuracy of translational initiation in recombinant gene expression systems.

37

Publications

2.8K

Citations

193

Authors

70

Institutions

Publications per year

2017–2026

10

Parents

Publications

37

Precise and reliable gene expression via standard transcription and translation initiation elements

Vivek K. Mutalik, Joao C. Guimaraes, Guillaume Cambray et al. · Nature Methods · 2013 · 826 citations · Full text

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Engineering circular RNA for enhanced protein production

Robert Chen, Sean K. Wang, Julia A. Belk et al. · Nature Biotechnology · 2022 · 424 citations · Full text

, , +17

Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region

Birgit Schauder, Helmut Blöcker, Ronald Frank et al. · Gene · 1987 · 223 citations

, , +16

β-Glucuronidase as a Sensitive and Versatile Reporter in Actinomycetes

Maksym Myronovskyi, Elisabeth Welle, Victor Fedorenko et al. · Applied and Environmental Microbiology · 2011 · 209 citations · Full text

, , +17

Tuning gene expression with synthetic upstream open reading frames

Joshua P. Ferreira, K. Wesley Overton, Clifford L. Wang · Proceedings of the National Academy of Sciences · 2013 · 136 citations · Full text

, , +17

1–5 of 37

Authors

193

  1. MC
    Michael C. Jewett

    Northwestern University, United States

    3 publications · 131 citations

    3

    h-index

  2. RG
    Rui Gan

    Peking University, China

    2 publications · 97 citations

    2

    h-index

  3. MH
    Morten H. H. Nørholm

    Novo Nordisk Foundation, Denmark

    2 publications · 62 citations

    2

    h-index

  4. JP
    Joshua P. Ferreira

    Stanford University, United States

    2 publications · 150 citations

    2

    h-index

  5. AS
    Alanna Schepartz

    Yale University, United States

    2 publications · 123 citations

    2

    h-index

1–5 of 193

Institutions

70

  1. Stanford University

    Stanford, United States

    5 h-index

    20 publications

    5.6K citations

  2. Northwestern University

    Evanston, United States

    3 h-index

    6 publications

    262 citations

  3. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    10 publications

    298 citations

  4. ETH Zurich

    Zurich, Switzerland

    2 h-index

    2 publications

    52 citations

  5. University of California, Berkeley

    Berkeley, United States

    2 h-index

    11 publications

    6.8K citations

  6. Yale University

    New Haven, United States

    2 h-index

    13 publications

    806 citations

  7. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    10 publications

    298 citations

  8. Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien

    Halle, Germany

    2 h-index

    7 publications

    1K citations

1–8 of 70

Venues

  1. Gene

    5 publications · 323 citations

    5

    h-index

  2. Nucleic Acids Research

    4 publications · 96 citations

    4

    h-index

  3. ACS Synthetic Biology

    2 publications · 62 citations

    2

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 190 citations

    2

    h-index

  5. Virology

    2 publications · 72 citations

    2

    h-index

1–5