Concepedia

Translation Factor Mutations

Translation Factor Mutations is a theoretical construct in molecular genetics that refers to heritable alterations in the genes encoding translation factors, which impair or modify their function in ribosomal initiation, elongation, or termination during protein synthesis.

51

Publications

2.5K

Citations

329

Authors

155

Institutions

Publications per year

2017–2026

13

Parents

Publications

51

Translation Initiator EIF4G1 Mutations in Familial Parkinson Disease

Marie‐Christine Chartier‐Harlin, Justus C. Dächsel, Carles Vilariño‐Güell et al. · The American Journal of Human Genetics · 2011 · 304 citations · Full text

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The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon.

Hye-Jin Yoon, Thomas F. Donahue · Molecular and Cellular Biology · 1992 · 168 citations · Full text

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The lethal mutation of the mouse wasted ( <i>wst</i> ) is a deletion that abolishes expression of a tissue-specific isoform of translation elongation factor 1α, encoded by the <i>Eef1a2</i> gene

Doreen Chambers, Josephine Peters, Catherine M. Abbott · Proceedings of the National Academy of Sciences · 1998 · 154 citations · Full text

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Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53 cDNAs in a mammalian translation system

Kim M. Keeling, David M. Bedwell · Journal of Molecular Medicine · 2002 · 143 citations

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A Regulatory Response to Ribosomal Protein Mutations Controls Translation, Growth, and Cell Competition

Chang Hyun Lee, Marianthi Kiparaki, Jorge Polo Blanco et al. · Developmental Cell · 2018 · 117 citations · Full text

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1–5 of 51

Authors

329

  1. LA
    Leif A. Isaksson

    Stockholm University, Sweden

    3 publications · 84 citations

    3

    h-index

  2. AK
    Amit Kumar

    Indian Institute of Technology Kanpur, India

    2 publications · 175 citations

    2

    h-index

  3. JP
    Jorge Polo Blanco

    University of Basel, Switzerland

    2 publications · 175 citations

    2

    h-index

  4. VC
    Victor Croitoru

    Stockholm University, Sweden

    2 publications · 43 citations

    2

    h-index

  5. VF
    Virginia Folgado

    Albert Einstein College of Medicine, United States

    2 publications · 175 citations

    2

    h-index

1–5 of 329

Institutions

155

  1. National Institutes of Health

    Bethesda, United States

    4 h-index

    16 publications

    575 citations

  2. Inserm

    Paris, France

    3 h-index

    11 publications

    2.6K citations

  3. Tel Aviv University

    Tel Aviv, Israel

    3 h-index

    14 publications

    1.1K citations

  4. Indiana University Bloomington

    Bloomington, United States

    3 h-index

    7 publications

    512 citations

  5. Albert Einstein College of Medicine

    Bronx, United States

    2 h-index

    18 publications

    1.5K citations

  6. Uppsala University

    Uppsala, Sweden

    2 h-index

    5 publications

    139 citations

  7. The University of Tokyo

    Tokyo, Japan

    2 h-index

    6 publications

    198 citations

  8. Stanford University

    Stanford, United States

    2 h-index

    11 publications

    135 citations

1–8 of 155

Venues

  1. Molecular and General Genetics MGG

    5 publications · 128 citations

    5

    h-index

  2. Molecular and Cellular Biology

    MCB · 3 publications · 289 citations

    3

    h-index

  3. PubMed

    Repository · 2 publications · 87 citations

    2

    h-index

  4. Nucleic Acids Research

    2 publications · 45 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 171 citations

    2

    h-index

1–5