David M. Bedwell

Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

Marybeth Howard, Raymond A. Frizzell, David M. Bedwell · Nature Medicine · 1996 · 496 citations

Pharmacy, Genetics, Pharmacotherapy +10

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

Marina Manuvakhova, Kim M. Keeling, David M. Bedwell · RNA · 2000 · 403 citations

Life Sciences, Molecular Biology, Pharmacology +17

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

David M. Bedwell, Anisa Kaenjak, Dale Benos et al. · Nature Medicine · 1997 · 334 citations

Life Sciences, Cell Biology, Genetics +9

The Efficiency of Translation Termination is Determined by a Synergistic Interplay Between Upstream and Downstream Sequences inSaccharomyces cerevisiae

Brian Bonetti, Lianwu Fu, James Moon et al. · Journal of Molecular Biology · 1995 · 322 citations

Life Sciences, Microbiology, Molecular Biology +14

The<i>spc</i>rtbosomal protein operon of<i>Eschenchia coli:</i>sequence and cotranscriptlon of the rlbosomal protein genes and a protein export gene

Douglas Pat Cerretti, Dennis R. Dean, G. R. Davis et al. · Nucleic Acids Research · 1983 · 259 citations · Full text

Life Sciences, Genetics, Microbiology +12