David M. Bedwell

Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

Raymond A. Frizzell, David M. Bedwell · Nature Medicine · 1996 · 491 citations

Antimicrobial Resistance Gene, Antibiotics, Medicine +8

Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system

Marina Manuvakhova, Kim M. Keeling, David M. Bedwell · RNA · 2000 · 398 citations

Engineering, Termination Codons, Molecular Biology +17

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

David M. Bedwell, Anisa Kaenjak, Dale Benos et al. · Nature Medicine · 1997 · 332 citations

Pathology, Pulmonary Pharmacology, Bronchial Neoplasm +5

The Efficiency of Translation Termination is Determined by a Synergistic Interplay Between Upstream and Downstream Sequences inSaccharomyces cerevisiae

Brian Bonetti, Lianwu Fu, James Moon et al. · Journal of Molecular Biology · 1995 · 314 citations

Systems Biology, Functional Genomics, Natural Sciences +11

The<i>spc</i>rtbosomal protein operon of<i>Eschenchia coli:</i>sequence and cotranscriptlon of the rlbosomal protein genes and a protein export gene

Douglas Pat Cerretti, Dennis R. Dean, G. R. Davis et al. · Nucleic Acids Research · 1983 · 257 citations · Full text

Genetics, Molecular Biology, Escherichia Coli +19