Concepedia

Transient Cofactor Intermediates

Transient Cofactor Intermediates is a mechanistic construct in enzymology that denotes a transient chemical species formed during cofactor-dependent catalysis wherein the cofactor covalently or non-covalently associates with a substrate or reaction intermediate, thereby facilitating group transfer or redox transformations through a short-lived, catalytically competent complex.

7

Publications

844

Citations

58

Authors

24

Institutions

Publications per year

2017–2026

2

Parents

Publications

7

Models for Nonheme Iron Intermediates:  Structural Basis for Tuning the Spin States of Fe(TPA) Complexes

Yan Zang, Jinheung Kim, Yanhong Dong et al. · Journal of the American Chemical Society · 1997 · 326 citations

, , +17

Transient intermediates of the methane monooxygenase catalytic cycle.

Seho Lee, Jeremy C. Nesheim, John D. Lipscomb · Journal of Biological Chemistry · 1993 · 289 citations · Full text

, , +15

Photoconversion Mechanism of the Second GAF Domain of Cyanobacteriochrome AnPixJ and the Cofactor Structure of Its Green-Absorbing State

Francisco Vélazquez Escobar, Tillmann Utesch, Rei Narikawa et al. · Biochemistry · 2013 · 73 citations

, , +17

High-resolution crystal structures of transient intermediates in the phytochrome photocycle

Melissa Carrillo, Suraj Pandey, Juan C Sanchez et al. · Structure · 2021 · 62 citations · Full text

, , +16

Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets

Zongtao Lin, Xie Wang, Katelyn A. Bustin et al. · ACS Central Science · 2021 · 45 citations · Full text

, , +16

1–5 of 7

Authors

58

  1. JK
    Jinheung Kim

    Ewha Womans University, South Korea

    1 publications · 326 citations

    1

    h-index

  2. EC
    Elin Claesson

    University of Gothenburg, Sweden

    1 publications · 62 citations

    1

    h-index

  3. SW
    Sebastian Westenhoff

    University of Gothenburg, Sweden

    1 publications · 62 citations

    1

    h-index

  4. PD
    Pierre Douzou

    Institut de Biologie Physico-Chimique, France

    1 publications · 30 citations

    1

    h-index

  5. ML
    Megan L. Matthews

    Pennsylvania State University, United States

    1 publications · 45 citations

    1

    h-index

1–5 of 58

Institutions

24

  1. Japan Synchrotron Radiation Research Institute

    Sayō, Japan

    1 h-index

    2 publications

    124 citations

  2. Max Planck Institute for Chemical Energy Conversion

    Mülheim, Germany

    1 h-index

    1 publications

    73 citations

  3. University of Pennsylvania

    Philadelphia, United States

    1 h-index

    7 publications

    315 citations

  4. SPring-8

    Sayō, Japan

    1 h-index

    7 publications

    434 citations

  5. Japan Science and Technology Agency

    Tokyo, Japan

    1 h-index

    2 publications

    146 citations

  6. Norwich Research Park

    Norwich, United Kingdom

    1 h-index

    2 publications

    38 citations

  7. University of Massachusetts Chan Medical School

    Worcester, United States

    1 h-index

    1 publications

    45 citations

  8. Technische Universität Berlin

    Berlin, Germany

    1 h-index

    4 publications

    292 citations

1–8 of 24

Venues

  1. FEBS Letters

    1 publications · 30 citations

    1

    h-index

  2. Biochemistry

    1 publications · 73 citations

    1

    h-index

  3. Inorganic Chemistry

    1 publications · 19 citations

    1

    h-index

  4. Journal of the American Chemical Society

    JACS · 1 publications · 326 citations

    1

    h-index

  5. Journal of Biological Chemistry

    JBC · 1 publications · 289 citations

    1

    h-index

1–5