Concepedia

Transgene Expression Optimization

Transgene Expression Optimization is a methodological framework in genetic engineering that systematically enhances the efficiency, specificity, and stability of transgene transcription and translation in host organisms through strategic modification of regulatory elements, codon usage, and genomic integration strategies.

127

Publications

7.8K

Citations

742

Authors

221

Institutions

Publications per year

2017–2026

22

Parents

Publications

127

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M. Valenzuela, Andrew Murphy, David Frendewey et al. · Nature Biotechnology · 2003 · 593 citations

, , +16

A Tn3 lacZ transposon for the random generation of beta‐galactosidase gene fusions: application to the analysis of gene expression in Agrobacterium.

Scott E. Stachel, Gynheung An, Carlos C. Flores et al. · The EMBO Journal · 1985 · 415 citations · Full text

, , +14

Optimized Gal4 genetics for permanent gene expression mapping in zebrafish

Martin Distel, Mario F. Wullimann, Reinhard W. Köster · Proceedings of the National Academy of Sciences · 2009 · 311 citations · Full text

, , +14

Comparative Analysis of Transposable Element Vector Systems in Human Cells

Ivana Grabundžija, Markus Irgang, Lajos Mátés et al. · Molecular Therapy · 2010 · 233 citations · Full text

, , +16

Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon

Ann E. Davidson, Darius Balciunas, Deanna Mohn et al. · Developmental Biology · 2003 · 225 citations

, , +16

1–5 of 127

Authors

742

  1. WW
    Wilfried Weber

    University of Freiburg, Germany

    4 publications · 220 citations

    4

    h-index

  2. MF
    Martin Fussenegger

    ETH Zurich, Switzerland

    4 publications · 220 citations

    4

    h-index

  3. RW
    Ralf Wagner

    University of Regensburg, Germany

    3 publications · 195 citations

    3

    h-index

  4. AJ
    Adrian J. Thrasher

    University College London, United Kingdom

    3 publications · 183 citations

    3

    h-index

  5. MG
    Manuel Grez

    Georg Speyer Haus, Germany

    3 publications · 162 citations

    3

    h-index

1–5 of 742

Institutions

221

  1. University College London

    London, United Kingdom

    5 h-index

    15 publications

    773 citations

  2. KU Leuven

    Leuven, Belgium

    4 h-index

    15 publications

    2.4K citations

  3. The University of Queensland

    Brisbane, Australia

    4 h-index

    13 publications

    617 citations

  4. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    25 publications

    1.1K citations

  5. ETH Zurich

    Zurich, Switzerland

    4 h-index

    15 publications

    1K citations

  6. Georg Speyer Haus

    Frankfurt am Main, Germany

    3 h-index

    12 publications

    674 citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    17 publications

    911 citations

  8. University of Regensburg

    Regensburg, Germany

    3 h-index

    8 publications

    440 citations

1–8 of 221

Venues

  1. Gene Therapy

    7 publications · 296 citations

    7

    h-index

  2. Molecular Therapy

    6 publications · 477 citations

    6

    h-index

  3. Nucleic Acids Research

    5 publications · 534 citations

    5

    h-index

  4. The Journal of Gene Medicine

    5 publications · 136 citations

    5

    h-index

  5. Protein Expression and Purification

    4 publications · 167 citations

    4

    h-index

1–5