David Frendewey

Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6

Raúl Mostoslavsky, Katrin F. Chua, David B. Lombard et al. · Cell · 2006 · 1.6K citations · Full text

Lifespan Extension, Chromatin, Genome Instability +10

Regulation of the Germinal Center Response by MicroRNA-155

To‐Ha Thai, Dinis Pedro Calado, Stefano Casola et al. · Science · 2007 · 1.5K citations

Individual Micrornas, Transcriptional Regulation, Developmental Biology +15

Multiple knockout mouse models reveal lincRNAs are required for life and brain development

Martin Sauvageau, Loyal A. Goff, Simona Lodato et al. · eLife · 2013 · 679 citations · Full text

Brain Development, Genetics, Epigenetics +18

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M. Valenzuela, Andrew Murphy, David Frendewey et al. · Nature Biotechnology · 2003 · 585 citations

Engineering, Transgenic Mouse Models, Molecular Biology +17

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

David Frendewey, Walter Keller · Cell · 1985 · 524 citations

Transcriptional Regulation, Pre-mrna Splicing, Natural Sciences +13