Concepedia

Toxin Modification

Toxin Modification is a scholarly contribution in the form of a method, model, framework, theory, construct, dataset, task, or metric that alters the structure, activity, or specificity of toxic compounds to achieve controlled or enhanced biological effects within the academic domain of Toxin Production.

510

Publications

28.9K

Citations

2.2K

Authors

637

Institutions

Publications per year

2017–2026

60

Parents

Publications

510

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

Dan Cassel, Thomas Pfeuffer · Proceedings of the National Academy of Sciences · 1978 · 913 citations · Full text

, , +16

Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands

Pavel I. Kitov, Joanna Sadowska, George L. Mulvey et al. · Nature · 2000 · 864 citations

, , +13

From genome to “venome”: Molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins

Bryan G. Fry · Genome Research · 2005 · 489 citations · Full text

, , +13

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming Toxin <i>Clostridium perfringens</i> Perfringolysin O:  An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy

Laura A. Shepard, Alejandro P. Heuck, Brian D. Hamman et al. · Biochemistry · 1998 · 318 citations

, , +17

A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS

Xiaoxue Wang, Dana M. Lord, Hsin-Yao Cheng et al. · Nature Chemical Biology · 2012 · 294 citations

, , +8

1–5 of 510

Authors

2.2K

  1. KA
    Klaus Aktories

    University of Freiburg, Germany

    18 publications · 1.6K citations

    17

    h-index

  2. IJ
    Ingo Just

    Medizinische Hochschule Hannover, Germany

    9 publications · 793 citations

    9

    h-index

  3. RJ
    R. John Collier

    Harvard University, United States

    8 publications · 1K citations

    8

    h-index

  4. AM
    A. M. Pappenheimer

    Harvard University, United States

    8 publications · 605 citations

    8

    h-index

  5. PB
    Patrice Boquet

    Inserm, France

    7 publications · 780 citations

    7

    h-index

1–5 of 2.2K

Institutions

637

  1. Harvard University

    Cambridge, United States

    18 h-index

    38 publications

    3.5K citations

  2. University of Freiburg

    Freiburg im Breisgau, Germany

    16 h-index

    79 publications

    6.2K citations

  3. National Institutes of Health

    Bethesda, United States

    12 h-index

    38 publications

    1.9K citations

  4. Inserm

    Paris, France

    11 h-index

    35 publications

    1.9K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    47 publications

    1.9K citations

  6. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    10 h-index

    49 publications

    2.2K citations

  7. Johannes Gutenberg University Mainz

    Mainz, Germany

    8 h-index

    20 publications

    829 citations

  8. Institut Pasteur

    Paris, France

    8 h-index

    22 publications

    1.5K citations

1–8 of 637

Venues

  1. Journal of Biological Chemistry

    JBC · 59 publications · 5.2K citations

    40

    h-index

  2. Biochemistry

    40 publications · 2.1K citations

    28

    h-index

  3. Infection and Immunity

    IAI · 18 publications · 1K citations

    18

    h-index

  4. European Journal of Biochemistry

    EJB · 15 publications · 750 citations

    15

    h-index

  5. Toxins

    13 publications · 288 citations

    13

    h-index

1–5