Concepedia

Toxic Protein Expression

Toxic Protein Expression is a phenomenon in heterologous protein expression wherein the recombinant protein adversely affects host cell viability or function due to intrinsic biological activity, improper folding, or metabolic burden, thereby impairing cellular processes and reducing expression efficiency.

133

Publications

7.4K

Citations

692

Authors

298

Institutions

Publications per year

2017–2026

32

Parents

Publications

133

α-Synuclein and neuronal cell death

Mark Cookson · Molecular Neurodegeneration · 2009 · 420 citations · Full text

, , +17

CpxP, a Stress-Combative Member of the Cpx Regulon

Paul N. Danese, Thomas J. Silhavy · Journal of Bacteriology · 1998 · 298 citations · Full text

, , +15

A single gene encodes a selective toxin causal to the development of tan spot of wheat.

Lynda M. Ciuffetti, Robert P. Tuori, Janey M. Gaventa · The Plant Cell · 1997 · 297 citations · Full text

, , +17

The toxicity of recombinant proteins in Escherichia coli: a comparison of overexpression in BL21(DE3), C41(DE3), and C43(DE3)

Laurence Dumon-Seignovert, Guillaume Cariot, Laurent Vuillard · Protein Expression and Purification · 2004 · 243 citations

, , +13

Insights into <b><i>Pseudomonas putida</i></b> KT2440 response to phenol‐induced stress by quantitative proteomics

Pedro M. Santos, Dirk Benndorf, Isabel Sá‐Correia · PROTEOMICS · 2004 · 223 citations

, , +17

1–5 of 133

Authors

692

  1. CR
    Célia R. Carlini

    Universidade Federal do Rio Grande do Sul, Brazil

    4 publications · 199 citations

    4

    h-index

  2. KM
    Kazuo Miyairi

    Hirosaki University, Japan

    2 publications · 30 citations

    2

    h-index

  3. NC
    Nicolas Charlet‐Berguerand

    Institut de génétique et de biologie moléculaire et cellulaire, France

    2 publications · 178 citations

    2

    h-index

  4. CB
    Christina Barja‐Fidalgo

    Universidade do Estado do Rio de Janeiro, Brazil

    2 publications · 72 citations

    2

    h-index

  5. LP
    Lars Poulsen

    Technical University of Denmark, Denmark

    2 publications · 89 citations

    2

    h-index

1–5 of 692

Institutions

298

  1. Inserm

    Paris, France

    9 h-index

    53 publications

    2.8K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    25 publications

    2K citations

  3. Harvard University

    Cambridge, United States

    4 h-index

    13 publications

    1K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    9 publications

    864 citations

  5. Université de Strasbourg

    Strasbourg, France

    3 h-index

    14 publications

    1.8K citations

  6. Peking University

    Beijing, China

    3 h-index

    12 publications

    478 citations

  7. Capital Medical University

    Beijing, China

    2 h-index

    6 publications

    99 citations

  8. Hirosaki University

    Hirosaki, Japan

    2 h-index

    5 publications

    78 citations

1–8 of 298

Venues

  1. Toxicon

    6 publications · 239 citations

    6

    h-index

  2. Applied and Environmental Microbiology

    AEM · 5 publications · 470 citations

    5

    h-index

  3. Scientific Reports

    4 publications · 146 citations

    4

    h-index

  4. PubMed

    Repository · 4 publications · 83 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 346 citations

    4

    h-index

1–5