Concepedia

Tmem16-dependent Externalization

TMEM16-Dependent Externalization is a biological mechanism of phosphatidylserine externalization that specifically relies on the activity of TMEM16 family scramblase proteins to facilitate the calcium-dependent translocation of phosphatidylserine from the inner to the outer leaflet of the plasma membrane.

16

Publications

2.6K

Citations

112

Authors

44

Institutions

Publications per year

2017–2026

9

Parents

Publications

16

Calcium-dependent phospholipid scrambling by TMEM16F

Jun Suzuki, Masato Umeda, Peter J. Sims et al. · Nature · 2010 · 994 citations · Full text

, , +11

X-ray structure of a calcium-activated TMEM16 lipid scramblase

Janine D. Brunner, Novandy K. Lim, Stephan Schenck et al. · Nature · 2014 · 477 citations

, , +14

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel

Mattia Malvezzi, Madhavan Chalat, Radmila Janjusevic et al. · Nature Communications · 2013 · 256 citations · Full text

, , +14

Atomistic insight into lipid translocation by a TMEM16 scramblase

Neville P. Bethel, Michael Grabe · Proceedings of the National Academy of Sciences · 2016 · 125 citations

, , +13

Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation

Ning Wu, Vitalij Černyšiov, Dominique Davidson et al. · Cell Reports · 2020 · 111 citations · Full text

, , +17

1–5 of 16

Authors

112

  1. AA
    Alessio Accardi

    Cornell University, United States

    3 publications · 436 citations

    3

    h-index

  2. AK
    Anant K. Menon

    Cornell University, United States

    3 publications · 436 citations

    3

    h-index

  3. ME
    Maria E. Falzone

    Cornell University, United States

    2 publications · 180 citations

    2

    h-index

  4. BL
    Byoung‐Cheol Lee

    Gwangju Institute of Science and Technology, South Korea

    2 publications · 180 citations

    2

    h-index

  5. JD
    Janine D. Brunner

    University of Zurich, Switzerland

    2 publications · 501 citations

    2

    h-index

1–5 of 112

Institutions

44

  1. Cornell University

    Ithaca, United States

    3 h-index

    22 publications

    3.1K citations

  2. University of Zurich

    Zurich, Switzerland

    2 h-index

    8 publications

    2.5K citations

  3. Harvard University

    Cambridge, United States

    2 h-index

    4 publications

    159 citations

  4. University of Cincinnati Medical Center

    Cincinnati, United States

    1 h-index

    2 publications

    222 citations

  5. Duke University Hospital

    Durham, United States

    1 h-index

    3 publications

    330 citations

  6. Medical University of Vienna

    Vienna, Austria

    1 h-index

    7 publications

    98 citations

  7. University of Pittsburgh

    Pittsburgh, United States

    1 h-index

    4 publications

    260 citations

  8. University of California, San Francisco

    San Francisco, United States

    1 h-index

    2 publications

    250 citations

1–8 of 44

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 297 citations

    3

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 103 citations

    2

    h-index

  3. Nature Communications

    2 publications · 357 citations

    2

    h-index

  4. Blood Cells Molecules and Diseases

    BCMD · 2 publications · 32 citations

    2

    h-index

  5. Nature

    2 publications · 1.5K citations

    2

    h-index

1–5