Concepedia

Thermostability Screening

Thermostability Screening is a method in protein engineering that identifies variants with enhanced structural resilience to elevated temperatures by assessing functional retention or conformational integrity after heat exposure, distinguishing it from other screening approaches through its specific focus on thermal resistance as a selection criterion.

92

Publications

5.4K

Citations

473

Authors

175

Institutions

Publications per year

2017–2026

25

Parents

Publications

92

Identification of thermolabile Escherichia coli proteins: prevention and reversion of aggregation by DnaK and ClpB

Axel Mogk, Toshifumi Tomoyasu, Pierre Goloubinoff et al. · The EMBO Journal · 1999 · 597 citations

, , +12

A Fluorescence-Detection Size-Exclusion Chromatography-Based Thermostability Assay for Membrane Protein Precrystallization Screening

Motoyuki Hattori, Ryan Hibbs, Eric Gouaux · Structure · 2012 · 269 citations · Full text

, , +13

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency 1 1Edited by J. A. Wells

Eric V. Shusta, Michele C. Kieke, Evan A. Parke et al. · Journal of Molecular Biology · 1999 · 231 citations

, , +7

High-Throughput Thermal Scanning: A General, Rapid Dye-Binding Thermal Shift Screen for Protein Engineering

Jason J. Lavinder, Sanjay B. Hari, Brandon J. Sullivan et al. · Journal of the American Chemical Society · 2009 · 220 citations · Full text

, , +15

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

David Bednář, Koen Beerens, Eva Šebestová et al. · PLoS Computational Biology · 2015 · 205 citations · Full text

, , +17

1–5 of 92

Authors

473

  1. MR
    Marvin R. Natowicz

    Cleveland Clinic, United States

    2 publications · 25 citations

    2

    h-index

  2. ZZ
    Zhangliang Zhu

    Tianjin University of Science and Technology, China

    2 publications · 103 citations

    2

    h-index

  3. IZ
    I Zalewski

    Eunice Kennedy Shriver Center, United States

    2 publications · 25 citations

    2

    h-index

  4. HQ
    Hui‐Min Qin

    Tianjin University of Science and Technology, China

    2 publications · 103 citations

    2

    h-index

  5. FL
    Fuping Lu

    Tianjin University of Science and Technology, China

    2 publications · 103 citations

    2

    h-index

1–5 of 473

Institutions

175

  1. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    19 publications

    688 citations

  2. University of Groningen

    Groningen, The Netherlands

    3 h-index

    13 publications

    573 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    9 publications

    591 citations

  4. University of California, Berkeley

    Berkeley, United States

    3 h-index

    5 publications

    179 citations

  5. Tianjin University of Science and Technology

    Tianjin, China

    3 h-index

    21 publications

    948 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    6 publications

    410 citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    3 h-index

    12 publications

    222 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    10 publications

    707 citations

1–8 of 175

Venues

  1. Journal of Agricultural and Food Chemistry

    4 publications · 108 citations

    4

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 3 publications · 72 citations

    3

    h-index

  3. 2

    h-index

  4. Applied and Environmental Microbiology

    AEM · 2 publications · 108 citations

    2

    h-index

  5. Protein Science

    PS · 2 publications · 144 citations

    2

    h-index

1–5