Concepedia

Tfiia Function

TFIIA Function is a molecular mechanism within the transcription initiation complex that stabilizes the binding of TFIID to the core promoter and enhances RNA polymerase II recruitment by preventing inhibitory interactions and facilitating pre-initiation complex assembly.

274

Publications

22.3K

Citations

873

Authors

241

Institutions

Publications per year

2017–2026

11

Parents

Publications

274

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

B. Franklin Pugh, Robert Tjian · Genes & Development · 1991 · 611 citations · Full text

, , +17

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

Keith Stringer, C. James Ingles, Jack Greenblatt · Nature · 1990 · 610 citations

, , +16

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

James A. Goodrich, Timothy Hoey, Catherine J. Thut et al. · Cell · 1993 · 409 citations

, , +16

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

Naoko Tanese, B. Franklin Pugh, Robert Tjian · Genes & Development · 1991 · 361 citations · Full text

, , +6

Redundant roles for the TFIID and SAGA complexes in global transcription

Tong Ihn Lee, Helen C. Causton, Frank C. P. Holstege et al. · Nature · 2000 · 360 citations

, , +13

1–5 of 274

Authors

873

  1. RG
    Robert G. Roeder

    Rockefeller University, United States

    28 publications · 3.4K citations

    24

    h-index

  2. RT
    Robert Tjian

    University of California, Berkeley, United States

    14 publications · 2.9K citations

    14

    h-index

  3. SH
    Steven Hahn

    Fred Hutch Cancer Center, United States

    13 publications · 1.8K citations

    13

    h-index

  4. DR
    Danny Reinberg

    Howard Hughes Medical Institute, United States

    12 publications · 1.4K citations

    12

    h-index

  5. PM
    Paul M. Lieberman

    The Wistar Institute, United States

    10 publications · 823 citations

    10

    h-index

1–5 of 873

Institutions

241

  1. Rockefeller University

    New York, United States

    30 h-index

    125 publications

    15.6K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    29 h-index

    107 publications

    15.9K citations

  3. Harvard University

    Cambridge, United States

    18 h-index

    46 publications

    4.2K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    64 publications

    3.5K citations

  5. Institut de génétique et de biologie moléculaire et cellulaire

    Illkirch-Graffenstaden, France

    14 h-index

    54 publications

    3.6K citations

  6. Inserm

    Paris, France

    13 h-index

    54 publications

    3.5K citations

  7. National Institutes of Health

    Bethesda, United States

    13 h-index

    51 publications

    6.2K citations

  8. University of California, Berkeley

    Berkeley, United States

    13 h-index

    41 publications

    6.1K citations

1–8 of 241

Venues

  1. Molecular and Cellular Biology

    MCB · 46 publications · 2.8K citations

    33

    h-index

  2. Journal of Biological Chemistry

    JBC · 49 publications · 2.8K citations

    32

    h-index

  3. Genes & Development

    26 publications · 4K citations

    26

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 20 publications · 1.4K citations

    20

    h-index

  5. Nucleic Acids Research

    19 publications · 563 citations

    15

    h-index

1–5