Concepedia

Target Hopping

Target Hopping is a computational strategy in pharmacophore alignment that enables the identification of bioactive compounds across distinct molecular targets by leveraging shared pharmacophoric features, thereby facilitating the discovery of novel target-activity relationships.

9

Publications

327

Citations

74

Authors

28

Institutions

Publications per year

2017–2026

4

Parents

Publications

9

From the protein's perspective: the benefits and challenges of protein structure-based pharmacophore modeling

Marijn P. A. Sanders, Ross McGuire, Luc Roumen et al. · MedChemComm · 2011 · 108 citations

, , +17

Identify drug repurposing candidates by mining the Protein Data Bank

Fabrice Moriaud, Stéphane Richard, Stewart A. Adcock et al. · Briefings in Bioinformatics · 2011 · 53 citations · Full text

, , +15

Numerical simulations of the controlled motion of a hopping asteroid lander on the regolith surface

Bin Cheng, Yang Yu, Hexi Baoyin · Monthly Notices of the Royal Astronomical Society · 2019 · 38 citations

, , +17

Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein–Protein Antagonists

Massimiliano Tognolini, Matteo Incerti, Daniele Pala et al. · ChemMedChem · 2013 · 30 citations

, , +12

Not Letting the Left Leg Know What the Right Leg is Doing

Frank H. Durgin, Laura F. Fox, Dong Hoon Kim · Psychological Science · 2003 · 29 citations

, , +11

1–5 of 9

Authors

74

  1. TK
    Theresa Klemm

    The University of Melbourne, Australia

    1 publications · 15 citations

    1

    h-index

  2. CT
    Christian Tiesmeyer

    Novartis Institutes for BioMedical Research

    1 publications · 15 citations

    1

    h-index

  3. LR
    Luc Roumen

    Vrije Universiteit Amsterdam, Netherlands

    1 publications · 108 citations

    1

    h-index

  4. IJ
    Iwan J. P. de Esch

    Vrije Universiteit Amsterdam, Netherlands

    1 publications · 108 citations

    1

    h-index

  5. MH
    Masayuki Haramura

    Chugai Pharma (United States), United States

    1 publications · 14 citations

    1

    h-index

1–5 of 74

Institutions

28

  1. Centre de Biologie Structurale

    Montpellier, France

    1 h-index

    1 publications

    53 citations

  2. University of Houston

    Houston, United States

    1 h-index

    1 publications

    15 citations

  3. University of Würzburg

    Würzburg, Germany

    1 h-index

    7 publications

    105 citations

  4. Vrije Universiteit Amsterdam

    Amsterdam, The Netherlands

    1 h-index

    3 publications

    324 citations

  5. Novartis (Switzerland)

    Basel, Switzerland

    1 h-index

    1 publications

    15 citations

  6. Tsinghua University

    Beijing, China

    1 h-index

    2 publications

    76 citations

  7. Molecular Discovery (United Kingdom)

    London, United Kingdom

    1 h-index

    9 publications

    144 citations

  8. Novartis Institutes for BioMedical Research

    Basel, Switzerland

    1 h-index

    1 publications

    15 citations

1–8 of 28

Venues

  1. ChemMedChem

    2 publications · 45 citations

    2

    h-index

  2. Psychological Science

    1 publications · 29 citations

    1

    h-index

  3. MedChemComm

    1 publications · 108 citations

    1

    h-index

  4. Briefings in Bioinformatics

    1 publications · 53 citations

    1

    h-index

  5. European Journal of Medicinal Chemistry

    1 publications · 24 citations

    1

    h-index

1–5