Luc Roumen

From the protein's perspective: the benefits and challenges of protein structure-based pharmacophore modeling

Marijn P. A. Sanders, Ross McGuire, Luc Roumen et al. · MedChemComm · 2011 · 105 citations

Drug Target, Biomolecular Structure Prediction, Reciprocal Ligand Space +22

Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics

Luc Roumen, Marijn P. A. Sanders, K. Pieterse et al. · Journal of Computer-Aided Molecular Design · 2007 · 65 citations · Full text

Switching from <i>S</i>- to <i>R-</i>Selectivity in the <i>Candida </i><i>antarctica</i> Lipase B-Catalyzed Ring-Opening of ω-Methylated Lactones:  Tuning Polymerizations by Ring Size

Jeroen van Buijtenen, Bart A. C. van As, M. A. L. Verbruggen et al. · Journal of the American Chemical Society · 2007 · 65 citations

Snooker: A Structure-Based Pharmacophore Generation Tool Applied to Class A GPCRs

Marijn P. A. Sanders, Stefan Verhoeven, Chris de Graaf et al. · Journal of Chemical Information and Modeling · 2011 · 59 citations

Drug Target, Quantitative Pharmacology, Peptide Science +21

Molecular Determinants of Ligand Binding Modes in the Histamine H₄Receptor: Linking Ligand-Based Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) Models to in Silico Guided Receptor Mutagenesis Studies

Enade Perdana Istyastono, Saskia Nijmeijer, Herman D. Lim et al. · Journal of Medicinal Chemistry · 2011 · 52 citations · Full text