Concepedia

T-cell Manufacturing

T-Cell Manufacturing is a biotechnological process that involves the isolation, genetic modification, and expansion of autologous or allogeneic T cells to produce chimeric antigen receptor (CAR) T cells for adoptive immunotherapy.

174

Publications

11.7K

Citations

1.6K

Authors

449

Institutions

Publications per year

2017–2026

143

Parents

Publications

174

T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells

Eugenia Zah, Meng-Yin Lin, Anne Silva-Benedict et al. · Cancer Immunology Research · 2016 · 612 citations · Full text

, , +17

Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies

Laurent Poirot, Brian Philip, Cécile Schiffer-Mannioui et al. · Cancer Research · 2015 · 596 citations

, , +17

Replacement of T-Cell Function by a T-Cell Product

Anneliese Schimpl, Eberhard Wecker · Nature New Biology · 1972 · 529 citations

, , +13

Manufacturing Validation of Biologically Functional T Cells Targeted to CD19 Antigen for Autologous Adoptive Cell Therapy

Daniel Hollyman, Jolanta Stefanski, Mark Przybylowski et al. · Journal of Immunotherapy · 2009 · 319 citations · Full text

, , +17

Rapid manufacturing of non-activated potent CAR T cells

Saba Ghassemi, Joseph S. Durgin, Selene Nuñez-Cruz et al. · Nature Biomedical Engineering · 2022 · 280 citations · Full text

, , +14

1–5 of 174

Authors

1.6K

  1. CH
    Carl H. June

    University of Pennsylvania, United States

    8 publications · 579 citations

    8

    h-index

  2. DF
    David F. Stroncek

    National Institutes of Health Clinical Center, United States

    8 publications · 532 citations

    8

    h-index

  3. BD
    Boro Dropulić

    Lentigen Technology (United States), United States

    6 publications · 372 citations

    6

    h-index

  4. RJ
    Rimas J. Orentas

    Medical College of Wisconsin, United States

    6 publications · 372 citations

    6

    h-index

  5. SL
    Steven L. Highfill

    National Institutes of Health Clinical Center, United States

    6 publications · 260 citations

    6

    h-index

1–5 of 1.6K

Institutions

449

  1. University of Pennsylvania

    Philadelphia, United States

    13 h-index

    84 publications

    9K citations

  2. Miltenyi Biotec (Germany)

    Cologne, Germany

    10 h-index

    49 publications

    3.4K citations

  3. University of Washington

    Seattle, United States

    8 h-index

    26 publications

    1.8K citations

  4. National Institutes of Health Clinical Center

    Bethesda, United States

    8 h-index

    55 publications

    3.2K citations

  5. Harvard University

    Cambridge, United States

    7 h-index

    38 publications

    3K citations

  6. University College London

    London, United Kingdom

    7 h-index

    35 publications

    5.2K citations

  7. Parker Institute for Cancer Immunotherapy

    San Francisco, United States

    7 h-index

    31 publications

    2.5K citations

  8. Stanford University

    Stanford, United States

    6 h-index

    55 publications

    5.1K citations

1–8 of 449

Venues

  1. Cytotherapy

    23 publications · 1.2K citations

    20

    h-index

  2. Frontiers in Immunology

    13 publications · 881 citations

    13

    h-index

  3. 10

    h-index

  4. Blood

    9 publications · 222 citations

    9

    h-index

  5. Journal for ImmunoTherapy of Cancer

    JITC · 7 publications · 247 citations

    7

    h-index

1–5