Laurent Poirot

Multiplex Genome-Edited T-cell Manufacturing Platform for “Off-the-Shelf” Adoptive T-cell Immunotherapies

Laurent Poirot, Brian Philip, Cécile Schiffer-Mannioui et al. · Cancer Research · 2015 · 577 citations

Cell Therapy, Adaptive Immune System, T-regulatory Cell +20

Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

Shannon J. Turley, Laurent Poirot, Masakazu Hattori et al. · The Journal of Experimental Medicine · 2003 · 342 citations · Full text

An oxygen sensitive self-decision making engineered CAR T-cell

Alexandre Juillerat, Alan Maréchal, Jean Marie Filhol et al. · Scientific Reports · 2017 · 218 citations · Full text

Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity

Laurent Poirot, Christophe Benoıst, Diane Mathis · Proceedings of the National Academy of Sciences · 2004 · 167 citations · Full text

Granulocyte–macrophage colony-stimulating factor inactivation in CAR T-cells prevents monocyte-dependent release of key cytokine release syndrome mediators

Mohit Sachdeva, Philippe Duchâteau, Stéphane Depil et al. · Journal of Biological Chemistry · 2019 · 148 citations · Full text

Inflammation, Cytokine, Immune Effector Functions +11