Concepedia

T Cell Activation Modulation

T Cell Activation Modulation is a methodological framework within immune checkpoint modulation that specifically regulates the signaling pathways and co-stimulatory signals governing T cell activation to fine-tune adaptive immune responses against pathological targets.

543

Publications

42.9K

Citations

4.3K

Authors

1.1K

Institutions

Publications per year

2017–2026

157

Parents

Publications

543

Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

François Ghiringhelli, Cédric Menard, Pierre E. Puig et al. · Cancer Immunology Immunotherapy · 2006 · 1.2K citations · Full text

, , +17

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra J. Corbett, Sidonia B. G. Eckle, Richard W. Birkinshaw et al. · Nature · 2014 · 882 citations

, , +16

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

Ziming Wang, Ethan G. Aguilar, Jesus I. Luna et al. · Nature Medicine · 2018 · 845 citations

, , +17

HIV‐1 replication is controlled at the level of T cell activation and proviral integration.

Mario Stevenson, Trevor L. Stanwick, Michael P. Dempsey et al. · The EMBO Journal · 1990 · 794 citations · Full text

, , +16

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

John R. Šedý, Maya Gavrieli, Karen G. Potter et al. · Nature Immunology · 2004 · 621 citations

, , +13

1–5 of 543

Authors

4.3K

  1. KT
    Kjetil Taskén

    University of Oslo, Norway

    7 publications · 386 citations

    7

    h-index

  2. EM
    Einar Martin Aandahl

    University of Oslo, Norway

    5 publications · 352 citations

    5

    h-index

  3. JP
    Josef Penninger

    Austrian Academy of Sciences, Austria

    4 publications · 637 citations

    4

    h-index

  4. GB
    Gottfried Baier

    Innsbruck Medical University, Austria

    4 publications · 354 citations

    4

    h-index

  5. TG
    Thomas Gruber

    Innsbruck Medical University, Austria

    4 publications · 354 citations

    4

    h-index

1–5 of 4.3K

Institutions

1.1K

  1. National Institutes of Health

    Bethesda, United States

    20 h-index

    112 publications

    10.7K citations

  2. Harvard University

    Cambridge, United States

    20 h-index

    80 publications

    8K citations

  3. Inserm

    Paris, France

    14 h-index

    93 publications

    12.5K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    12 h-index

    52 publications

    12.4K citations

  5. National Cancer Institute

    Bethesda, United States

    12 h-index

    62 publications

    4.4K citations

  6. Center for Cancer Research

    Bethesda, United States

    11 h-index

    66 publications

    4.1K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    38 publications

    2.4K citations

  8. University of California, San Francisco

    San Francisco, United States

    10 h-index

    28 publications

    5.4K citations

1–8 of 1.1K

Venues

  1. The Journal of Immunology

    JI · 95 publications · 7.6K citations

    47

    h-index

  2. European Journal of Immunology

    EJI · 23 publications · 1.4K citations

    18

    h-index

  3. Nature Immunology

    16 publications · 3.4K citations

    16

    h-index

  4. Cancer Immunology Immunotherapy

    14 publications · 1.7K citations

    14

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1K citations

    13

    h-index

1–5