Concepedia

Super-enhancer Networks

Super-Enhancer Networks is a computational framework that integrates genomewide epigenetic and transcriptional data to model large clusters of enhancers with exceptionally high regulatory activity, distinguishing it from general enhancer network models by prioritizing cell-identity-associated genes through coordinated, high-intensity transcriptional control.

78

Publications

10K

Citations

989

Authors

374

Institutions

Publications per year

2017–2026

70

Parents

Publications

78

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.3K citations · Full text

, , +16

Super-enhancers delineate disease-associated regulatory nodes in T cells

Golnaz Vahedi, Yuka Kanno, Yasuko Furumoto et al. · Nature · 2015 · 404 citations · Full text

, , +14

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

Xiaoyang Zhang, Peter S. Choi, Joshua M. Francis et al. · Nature Genetics · 2015 · 360 citations · Full text

, , +14

The long noncoding RNA <i>Wisper</i> controls cardiac fibrosis and remodeling

Rudi Micheletti, Isabelle Plaisance, Brian J. Abraham et al. · Science Translational Medicine · 2017 · 337 citations · Full text

, , +14

Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis

Hiroshi Suzuki, Richard A. Young, Phillip A. Sharp · Cell · 2017 · 283 citations · Full text

, , +14

1–5 of 78

Authors

989

  1. RA
    Richard A. Young

    Whitehead Institute for Biomedical Research, United States

    6 publications · 917 citations

    6

    h-index

  2. DL
    De‐Chen Lin

    Cedars-Sinai Medical Center, United States

    6 publications · 381 citations

    6

    h-index

  3. BJ
    Brian J. Abraham

    Whitehead Institute for Biomedical Research, United States

    5 publications · 4.8K citations

    5

    h-index

  4. HW
    Henry W. Long

    Dana-Farber Cancer Institute, United States

    4 publications · 210 citations

    4

    h-index

  5. CR
    Christopher R. Vakoc

    Cold Spring Harbor Laboratory, United States

    3 publications · 377 citations

    3

    h-index

1–5 of 989

Institutions

374

  1. Dana-Farber Cancer Institute

    Boston, United States

    10 h-index

    54 publications

    9.2K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    10 h-index

    18 publications

    6.6K citations

  3. Whitehead Institute for Biomedical Research

    Cambridge, United States

    7 h-index

    26 publications

    41.7K citations

  4. Sun Yat-sen University

    Guangzhou, China

    7 h-index

    49 publications

    1.6K citations

  5. Harvard University

    Cambridge, United States

    6 h-index

    27 publications

    1.7K citations

  6. Broad Institute

    Cambridge, United States

    6 h-index

    13 publications

    2.5K citations

  7. Cedars-Sinai Medical Center

    Los Angeles, United States

    5 h-index

    42 publications

    2.9K citations

  8. St. Jude Children's Research Hospital

    Memphis, United States

    5 h-index

    5 publications

    542 citations

1–8 of 374

Venues

  1. Nature Communications

    9 publications · 660 citations

    9

    h-index

  2. Nucleic Acids Research

    6 publications · 316 citations

    6

    h-index

  3. Cell Reports

    4 publications · 230 citations

    4

    h-index

  4. Oncogene

    3 publications · 151 citations

    3

    h-index

  5. Leukemia

    3 publications · 262 citations

    3

    h-index

1–5